Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. 26719882

2016

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function. 22835832

2012

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer. 23083876

2012

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR R46Q mutation in the succinate dehydrogenase B gene (SDHB) in a Japanese family with both abdominal and thoracic paraganglioma following metastasis. 18362451

2008

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Genetic mutation screening in an italian cohort of nonsyndromic pheochromocytoma/paraganglioma patients. 17102082

2006

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Genetic testing in pheochromocytoma or functional paraganglioma. 16314641

2005

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. 15328326

2004

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. 12618761

2003

dbSNP: rs772551056
rs772551056
T 0.800 CausalMutation CLINVAR Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003

dbSNP: rs772551056
rs772551056
0.800 GeneticVariation UNIPROT