Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
---|---|---|---|---|---|---|---|---|---|---|
|
T | 0.800 | CausalMutation | CLINVAR | SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. | 26719882 | 2016 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Structural and functional consequences of succinate dehydrogenase subunit B mutations. | 25972245 | 2015 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. | 23282968 | 2013 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function. | 22835832 | 2012 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer. | 23083876 | 2012 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | R46Q mutation in the succinate dehydrogenase B gene (SDHB) in a Japanese family with both abdominal and thoracic paraganglioma following metastasis. | 18362451 | 2008 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Genetic mutation screening in an italian cohort of nonsyndromic pheochromocytoma/paraganglioma patients. | 17102082 | 2006 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Genetic testing in pheochromocytoma or functional paraganglioma. | 16314641 | 2005 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. | 15328326 | 2004 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. | 12618761 | 2003 |
|||
|
T | 0.800 | CausalMutation | CLINVAR | Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. | 14500403 | 2003 |
|||
|
0.800 | GeneticVariation | UNIPROT |