rs1057518731
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1057518733
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1057520529
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1131692245
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs113993959
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1555580263
|
|
GAGGTAGAACCTTATCTGCCATCTTC |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs74597325
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs76992529
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs879253740
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs796051877
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
c.1437G>A intron 9 substitution on acid α-glucosidase gene associated with classic infantile-onset Pompe disease phenotype.
|
26160551 |
2015 |
rs213950
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Caucasian and African American children with pneumonia were genotyped for the most common variants reported to affect cystic fibrosis transmembrane conductance regulator function, the p.508del mutation, the (TG)mTn variable repeat region, and the M470V polymorphism in the cystic fibrosis transmembrane conductance regulator gene.
|
22890249 |
2012 |
rs601338
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For FUT2 SNP rs601338, the risk ratios for ≥1 bout of diarrhea during ages 6-12 months and ages 12-24 months per additional risk (G) allele were 1.23 (95% confidence interval [CI], 1.08-1.4; P = .002) and 1.41 (95% CI, 1.24-1.61; P = 1.7 × 10-7), respectively; the risk ratio for ≥1 diagnosis of a lower respiratory illness (ie, pneumonia or bronchiolitis) during ages 12-24 months per additional G allele was 2.66 (95% CI, 1.64-4.3; P = .00007).
|
30376117 |
2019 |
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, the cosegregating TLR4 polymorphisms Asp299Gly and Thr399Ile were independent risk factors for the development of both sepsis and pneumonia (OR: 3.55; 95% CI: 1.21-10.4, P=0.021 and OR: 3.57, 95% CI: 1.3-9.86, P=0.014, respectively).
|
25427560 |
2015 |
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Furthermore, the cosegregating TLR4 polymorphisms Asp299Gly and Thr399Ile were independent risk factors for the development of both sepsis and pneumonia (OR: 3.55; 95% CI: 1.21-10.4, P=0.021 and OR: 3.57, 95% CI: 1.3-9.86, P=0.014, respectively).
|
25427560 |
2015 |
rs4957796
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study.
|
25533491 |
2015 |
rs4251961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Higher plasma IL-1ra was associated with an increased risk of infection (other than pneumonia), and the minor C allele of rs4251961 was independently associated with a decreased risk of infection (other than pneumonia).
|
24233813 |
2014 |
rs4957796
|
|
|
0.710 |
GeneticVariation |
BEFREE |
In conclusion, FER rs4957796 might act as a prognostic variable for survival in patients with severe ARDS due to pneumonia.
|
28851893 |
2017 |
rs1800795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In intensive care unit patients, the TNF-α -308A allele and the IL-6 rs1800795 allele variants were susceptibility risk factors for septic shock induced by pneumonia.
|
26025100 |
2015 |
rs1800629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we aim to investigate the association of promoter-region polymorphisms IL-6 (-174G/C) rs1800795 and TNF-α (-308G/A) rs1800629 with pneumonia-induced sepsis.
|
26025100 |
2015 |
rs17615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One patient had 3 homozygous nonsynonymous variations of the complement receptor 2 (CR2) gene distributed in exons 10 (c.1916G>A, p.S639N) and 11 (c.1987T>C, p.S663P and c.2012G>A, p.R671H) with high frequency.This case series suggests that fungi are important respiratory pathogens in children with HIES and should be considered in cases of pneumonia in this population.
|
29620631 |
2018 |
rs4308977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One patient had 3 homozygous nonsynonymous variations of the complement receptor 2 (CR2) gene distributed in exons 10 (c.1916G>A, p.S639N) and 11 (c.1987T>C, p.S663P and c.2012G>A, p.R671H) with high frequency.This case series suggests that fungi are important respiratory pathogens in children with HIES and should be considered in cases of pneumonia in this population.
|
29620631 |
2018 |
rs17616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One patient had 3 homozygous nonsynonymous variations of the complement receptor 2 (CR2) gene distributed in exons 10 (c.1916G>A, p.S639N) and 11 (c.1987T>C, p.S663P and c.2012G>A, p.R671H) with high frequency.This case series suggests that fungi are important respiratory pathogens in children with HIES and should be considered in cases of pneumonia in this population.
|
29620631 |
2018 |
rs5743708
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Patients carrying the TLR2 SNP rs5743708 (R753Q, GA/AA genotype, n = 12) also revealed a significantly higher susceptibility to pneumonia including IFD.
|
26963509 |
2016 |
rs1130866
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Previous studies have indicated that a SP-B 1580C/T polymorphism (SNP rs1130866) was associated with lung diseases including pneumonia.
|
26620227 |
2016 |
rs1412125
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs at the rs1412125 and rs2249825 loci of HMGB1 are associated with pneumonia in terms of susceptibility, severity, and inflammatory response.
|
30562142 |
2019 |