Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4957796
rs4957796
FER
0.710 GeneticVariation BEFREE In conclusion, FER rs4957796 might act as a prognostic variable for survival in patients with severe ARDS due to pneumonia. 28851893

2017

dbSNP: rs4957796
rs4957796
FER
0.710 GeneticVariation GWASCAT Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study. 25533491

2015

dbSNP: rs796051877
rs796051877
GAA
A 0.700 CausalMutation CLINVAR c.1437G>A intron 9 substitution on acid α-glucosidase gene associated with classic infantile-onset Pompe disease phenotype. 26160551

2015

dbSNP: rs1057518731
rs1057518731
T 0.700 CausalMutation CLINVAR

dbSNP: rs1057518733
rs1057518733
G 0.700 CausalMutation CLINVAR

dbSNP: rs1057520529
rs1057520529
T 0.700 CausalMutation CLINVAR

dbSNP: rs1131692245
rs1131692245
T 0.700 CausalMutation CLINVAR

dbSNP: rs113993959
rs113993959
T 0.700 CausalMutation CLINVAR

dbSNP: rs1555580263
rs1555580263
GAGGTAGAACCTTATCTGCCATCTTC 0.700 CausalMutation CLINVAR

dbSNP: rs74597325
rs74597325
T 0.700 CausalMutation CLINVAR

dbSNP: rs76992529
rs76992529
TTR
A 0.700 CausalMutation CLINVAR

dbSNP: rs879253740
rs879253740
G 0.700 CausalMutation CLINVAR

dbSNP: rs5743708
rs5743708
0.020 GeneticVariation BEFREE Patients carrying the TLR2 SNP rs5743708 (R753Q, GA/AA genotype, n = 12) also revealed a significantly higher susceptibility to pneumonia including IFD. 26963509

2016

dbSNP: rs4986791
rs4986791
0.020 GeneticVariation BEFREE Furthermore, the cosegregating TLR4 polymorphisms Asp299Gly and Thr399Ile were independent risk factors for the development of both sepsis and pneumonia (OR: 3.55; 95% CI: 1.21-10.4, P=0.021 and OR: 3.57, 95% CI: 1.3-9.86, P=0.014, respectively). 25427560

2015

dbSNP: rs5743708
rs5743708
0.020 GeneticVariation BEFREE The presence of the TLR2 Arg753Gln polymorphism was significantly associated with pneumonia in AML patients (odds ratio (OR): 10.78; 95% confidence interval (CI): 2.0-58.23; P=0.006). 25427560

2015

dbSNP: rs4986791
rs4986791
0.020 GeneticVariation BEFREE This case-control study evaluated the prevalence of D299G/T399I polymorphisms in Mexican patients with IAI and/or pneumonia and in healthy controls. 23871732

2013

dbSNP: rs1045411
rs1045411
0.010 GeneticVariation BEFREE To investigate the relationship between the high mobility group box protein B1 (HMGB1) single nucleotide polymorphisms (SNPs) rs1412125, rs2249825, and rs1045411 with pneumonia in terms of susceptibility, severity, and inflammatory response. 30562142

2019

dbSNP: rs1412125
rs1412125
0.010 GeneticVariation BEFREE SNPs at the rs1412125 and rs2249825 loci of HMGB1 are associated with pneumonia in terms of susceptibility, severity, and inflammatory response. 30562142

2019

dbSNP: rs2249825
rs2249825
0.010 GeneticVariation BEFREE SNPs at the rs1412125 and rs2249825 loci of HMGB1 are associated with pneumonia in terms of susceptibility, severity, and inflammatory response. 30562142

2019

dbSNP: rs601338
rs601338
0.010 GeneticVariation BEFREE For FUT2 SNP rs601338, the risk ratios for ≥1 bout of diarrhea during ages 6-12 months and ages 12-24 months per additional risk (G) allele were 1.23 (95% confidence interval [CI], 1.08-1.4; P = .002) and 1.41 (95% CI, 1.24-1.61; P = 1.7 × 10-7), respectively; the risk ratio for ≥1 diagnosis of a lower respiratory illness (ie, pneumonia or bronchiolitis) during ages 12-24 months per additional G allele was 2.66 (95% CI, 1.64-4.3; P = .00007). 30376117

2019

dbSNP: rs17615
rs17615
CR2
0.010 GeneticVariation BEFREE One patient had 3 homozygous nonsynonymous variations of the complement receptor 2 (CR2) gene distributed in exons 10 (c.1916G>A, p.S639N) and 11 (c.1987T>C, p.S663P and c.2012G>A, p.R671H) with high frequency.This case series suggests that fungi are important respiratory pathogens in children with HIES and should be considered in cases of pneumonia in this population. 29620631

2018

dbSNP: rs17616
rs17616
CR2
0.010 GeneticVariation BEFREE One patient had 3 homozygous nonsynonymous variations of the complement receptor 2 (CR2) gene distributed in exons 10 (c.1916G>A, p.S639N) and 11 (c.1987T>C, p.S663P and c.2012G>A, p.R671H) with high frequency.This case series suggests that fungi are important respiratory pathogens in children with HIES and should be considered in cases of pneumonia in this population. 29620631

2018

dbSNP: rs4308977
rs4308977
CR2
0.010 GeneticVariation BEFREE One patient had 3 homozygous nonsynonymous variations of the complement receptor 2 (CR2) gene distributed in exons 10 (c.1916G>A, p.S639N) and 11 (c.1987T>C, p.S663P and c.2012G>A, p.R671H) with high frequency.This case series suggests that fungi are important respiratory pathogens in children with HIES and should be considered in cases of pneumonia in this population. 29620631

2018

dbSNP: rs2294021
rs2294021
0.010 GeneticVariation BEFREE The relationships between FOXP3 rs3761547, rs3761548, rs3761549, rs2232365, rs2280883, and CCDC22 rs2294021 polymorphisms and clinical outcomes such as acute rejection, TAC-induced acute nephrotoxicity, and pneumonia were investigated by using Kaplan-Meier estimates and multivariate Cox regression analysis. 27747372

2017

dbSNP: rs1130866
rs1130866
0.010 GeneticVariation BEFREE Previous studies have indicated that a SP-B 1580C/T polymorphism (SNP rs1130866) was associated with lung diseases including pneumonia. 26620227

2016