Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1181860747
rs1181860747
0.060 GeneticVariation BEFREE Our findings suggest that IRS-1 Gly972Arg polymorphism is associated with PCOS in the Caucasian ethnicity, and IRS-2 Gly1057Asp polymorphism is correlated with PCOS in the Asian ethnicity. 27098445

2016

dbSNP: rs1181860747
rs1181860747
0.060 GeneticVariation BEFREE We found significant difference in the genotypic distribution of IRS-2 gene Gly1057Asp between the PCOS group and the control group (p = 0.004). 25310961

2014

dbSNP: rs1181860747
rs1181860747
0.060 GeneticVariation BEFREE DNA was extracted from whole blood samples for genotyping and detection of IRS-2 Gly1057Asp polymorphism in 129 PCOS women and 109 control women. 21801267

2011

dbSNP: rs1181860747
rs1181860747
0.060 GeneticVariation BEFREE The present study was undertaken to determine whether IRS-1 Gly972Arg and IRS-2 Gly1057Asp influence hormonal and metabolic characteristics in Greek patients with polycystic ovary syndrome (PCOS) and controls. 20210696

2010

dbSNP: rs1181860747
rs1181860747
0.060 GeneticVariation BEFREE These results suggest that the IRS-2 Gly(1057)Asp polymorphism influences blood glucose levels in nondiabetic white and African-American women with PCOS. 12213887

2002

dbSNP: rs1181860747
rs1181860747
0.060 GeneticVariation BEFREE Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome. 11522686

2001