|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> Genetic variants of PCOS (rs13405728 in <i>LHCGR</i> gene; rs13429458 in <i>THADA</i> gene and rs2479106 in <i>DENND1A</i> gene) may not be involved in the development of preeclampsia in Han Chinese women.
|
29727258 |
2019 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
It was suggested that the TT genotype of LHCGR rs13405728, CC genotype of THADA rs12478601 and AG + GG genotype of DENND1A rs2479106 had poor outcomes of IVF-ET in treating PCOS.
|
30844144 |
2019 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Setting homozygous wild-type genotype carrier as reference, rs10818854 and rs10986105 were associated with increased risk of PCOS, which persisted after controlling for key covariates, while reduced PCOS risk was seen with only rs2479106 under the additive model.
|
29325736 |
2018 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This meta-analysis suggested that rs2479106 and rs10818854 polymorphisms in the DENND1A gene were associated with increased risk of PCOS.
|
26757598 |
2016 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The outcome was that the minor allele frequencies of SNPs rs10818854, rs2479106</span>, and rs10986105 were similar between women with PCOS and control women (P>0.05), even before correcting for multiple testing, and none of the tested DENND1A SNPs were associated with PCOS under co-dominant, dominant, or recessive genetic models.
|
25626177 |
2015 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our previous research had identified three susceptibility loci (rs2479106, DENND1A; rs13405728, LHCGR; rs13429458, THADA) for PCOS in Han Chinese women.
|
25978310 |
2015 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Using a dominant model, the GG + AG group for rs2479106 in DENND1A was associated with elevated serum insulin levels 2 h after a glucose load in the patients with PCOS (P = 0.02).
|
23208300 |
2013 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The aim of this study was to explore the polycystic ovary syndrome (PCOS) related single nucleotide polymorphisms (SNPs) rs13405728 (in gene LHCGR), rs13429458 (in gene THADA) and rs2479106 (in gene DENND1A) in women with endometrial carcinoma.
|
22902918 |
2012 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Other risk variants at 2p16.3 (rs13405728), 2p21 (rs12468394, rs12478601, and rs13429458), and 9q33.3 (rs2479106), or variants correlated with them, did not associate with PCOS.
|
22547425 |
2012 |
|
rs2479106
|
|
G |
0.900 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.
|
22885925 |
2012 |
|
rs2479106
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.
|
22885925 |
2012 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The rs2479106 G allele was associated with decreased PCOS susceptibility, thus confirming previously reported findings of association between rs2479106 and PCOS.
|
22504079 |
2012 |
|
rs2479106
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
We identified strong evidence of associations between PCOS and three loci: 2p16.3 (rs13405728; combined P-value by meta-analysis P(meta) = 7.55 × 10⁻²¹, odds ratio (OR) 0.71); 2p21 (rs13429458, P(meta) = 1.73 × 10⁻²³, OR 0.67); and 9q33.3 (rs2479106, P(meta) = 8.12 × 10⁻¹⁹, OR 1.34).
|
21151128 |
2011 |
|
rs2479106
|
|
G |
0.900 |
GeneticVariation |
GWASDB |
We identified strong evidence of associations between PCOS and three loci: 2p16.3 (rs13405728; combined P-value by meta-analysis P(meta) = 7.55 × 10⁻²¹, odds ratio (OR) 0.71); 2p21 (rs13429458, P(meta) = 1.73 × 10⁻²³, OR 0.67); and 9q33.3 (rs2479106, P(meta) = 8.12 × 10⁻¹⁹, OR 1.34).
|
21151128 |
2011 |
|
rs2479106
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We identified strong evidence of associations between PCOS and three loci: 2p16.3 (rs13405728; combined P-value by meta-analysis P(meta) = 7.55 × 10⁻²¹, odds ratio (OR) 0.71); 2p21 (rs13429458, P(meta) = 1.73 × 10⁻²³, OR 0.67); and 9q33.3 (rs2479106, P(meta) = 8.12 × 10⁻¹⁹, OR 1.34).
|
21151128 |
2011 |