Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.060 | GeneticVariation | BEFREE | The APC p.I1307K gene variant is an important risk factor for colorectal neoplasia in average risk Ashkenazi Jews. | 23896379 | 2013 |
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0.060 | GeneticVariation | BEFREE | An APC mutation (I1307K) was found in an index case of a non-Jewish woman and her son with attenuated familial adenomatous polyposis (A-FAP) and no family history of cancer. | 22180177 | 2012 |
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|
0.060 | GeneticVariation | BEFREE | An APC mutation (I1307K) was found in an index case of a non-Jewish woman and her son with attenuated familial adenomatous polyposis (A-FAP) and no family history of cancer. | 22180177 | 2012 |
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0.060 | GeneticVariation | BEFREE | The characterization of somatic APC mutations in colonic adenomas and carcinomas in Ashkenazi Jews with the APC I1307K variant using linkage disequilibrium. | 12533826 | 2003 |
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0.060 | GeneticVariation | BEFREE | The characterization of somatic APC mutations in colonic adenomas and carcinomas in Ashkenazi Jews with the APC I1307K variant using linkage disequilibrium. | 12533826 | 2003 |
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|
0.060 | GeneticVariation | BEFREE | The authors believe the findings of the current study broaden the known spectrum of ethnic groups in which the APC I1307K mutation is prevalent. | 10679643 | 2000 |
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0.060 | GeneticVariation | BEFREE | The authors believe the findings of the current study broaden the known spectrum of ethnic groups in which the APC I1307K mutation is prevalent. | 10679643 | 2000 |
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0.060 | GeneticVariation | BEFREE | The vast majority of APC I1307K somatic mutations consisted of a single adenine insertion (insA) involving the variant (A)8 tract. | 9751605 | 1998 |
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0.060 | GeneticVariation | BEFREE | The vast majority of APC I1307K somatic mutations consisted of a single adenine insertion (insA) involving the variant (A)8 tract. | 9751605 | 1998 |