rs121913430
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
|
25157968 |
2014 |
rs138213197
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours.
|
29259341 |
2017 |
rs138213197
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers.
|
28186998 |
2017 |
rs138213197
|
|
|
0.030 |
GeneticVariation |
BEFREE |
PSA testing, six-core biopsy, genetic counselling and mutation analysis for French Canadian founder mutations in the BRCA1 and BRCA2 genes, histopathological review of tumour tissue from family members, examination of loss of heterozygosity at the BRCA2 gene locus, immunohistochemistry to determine the expression of the ERG nuclear oncoprotein in prostate tumours, genotyping with eight selected risk-associated single nucleotide polymorphisms, Doppler ultrasonography of the leg, CT of the abdomen and pelvis with intravenous and oral contrast, chest CT with intravenous contrast for the assessment of metastatic prostate cancer, genetic testing for the G84E variant in the HOXB13 gene.
|
23318356 |
2013 |
rs137852578
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The gene expression profile of AR-E231G prostate tissue from 12-week-old mice was compared to an equivalent profile from mice expressing the AR-T857A receptor variant (analogous to the AR-T877A variant in LNCaP cells), which do not develop prostate tumors.
|
22275114 |
2012 |
rs486907
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A novel gammaretrovirus named xenotropic murine leukemia virus-related virus (XMRV) has been recently identified and found to have a prevalence of 40% in prostate tumor samples from American patients carrying a homozygous R462Q mutation in the RNaseL gene.
|
19835577 |
2009 |
rs486907
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.
|
16609730 |
2006 |
rs137852578
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Human LNCaP cells, extensively used as a model for androgen-dependent prostate tumor, express the androgen receptor (AR) mutant T877A promiscuously transactivated by estrogens and other ligands, which may further facilitate cancer progression.
|
12391264 |
2002 |
rs148609049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It was found to be an eQTL for ANO7 (Linear model p-values for Finnish patients p = 0.009; Camcap prostate tumor p = 2.53E-06; Stockholm prostate tumor cohort p = 1.53E-13). rs148609049 was not associated with risk, but was related to shorter survival (HR 1.56; 95% CI 1.03-2.36).
|
30157291 |
2018 |
rs368234815
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We show that the <i>IFNL4</i> rs368234815-ΔG allele was significantly associated with IRDS in prostate tumors and overall survival of AA patients.
|
30012562 |
2018 |
rs1057519864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CDK4/6i was also effective in prostate tumor models expressing the AR-V7 variant or the AR F876L mutation, both of which are associated with treatment resistance.
|
28209757 |
2017 |
rs1060501201
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers.
|
28186998 |
2017 |
rs1197734477
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers.
|
28186998 |
2017 |
rs2155222
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The findings indicate the functionality of the PrCa death-predisposing SNPs rs143975731, rs12277366, rs2155225, and rs2155222 as DGAT2 regulators in prostate tumors.© 2016 Wiley Periodicals, Inc.
|
27113481 |
2016 |
rs1057519971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We sequenced the SPOP gene to identify somatic mutations in 49 AA prostate tumors and identified three missense mutations (p.Y87C, p.F102S, and p.G111E) in five AA prostate tumors (10%) and one synonymous variant (p.I106I) in one tumor.
|
24994784 |
2015 |
rs339331
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Finally, we observe a significant association between the risk-associated T allele at rs339331 and increased RFX6 mRNA levels in human prostate tumors.
|
24390282 |
2014 |
rs375118292
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of the prostate tumor from this individual verified the presence of heterozygous N296I as well as an ERG fusion.
|
24796539 |
2014 |
rs727502792
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of the prostate tumor from this individual verified the presence of heterozygous N296I as well as an ERG fusion.
|
24796539 |
2014 |
rs746001963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of the prostate tumor from this individual verified the presence of heterozygous N296I as well as an ERG fusion.
|
24796539 |
2014 |
rs1057519912
|
|
|
0.010 |
GeneticVariation |
BEFREE |
So far, the recently reported MED12 p.L1224F mutation could not be validated in our unselected cohort of prostate tumours.
|
23661306 |
2013 |
rs16861209
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue.
|
21960694 |
2011 |
rs17366568
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue.
|
21960694 |
2011 |
rs182052
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue.
|
21960694 |
2011 |
rs266729
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue.
|
21960694 |
2011 |
rs3774261
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue.
|
21960694 |
2011 |