This study aims to assess whether the association between the non-susceptibility allelic variants of IL12B single-nucleotide polymorphism (SNPs) rs3212227 and rs6887695, IL23R SNPs rs11209026 and rs7530511, IL6 SNP rs1800795 and HLA-Cw6 could be correlated with decreased risk for psoriasis.
The aim of this study of 406 patients with psoriasis and 203 healthy controls was to evaluate the association between the IL6 -174G>C (rs1800795) polymorphism and psoriasis susceptibility, as well as treatment efficacy.