Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs33980500
rs33980500
0.850 GeneticVariation BEFREE Collectively, these results implicate NETs and the Act1 D10N variant in human Th17 induction from peripheral blood mononuclear cells, with ramifications for immunogenetic studies of psoriasis and other autoimmune diseases. 30528823

2019

dbSNP: rs33980500
rs33980500
0.850 GeneticVariation BEFREE Collectively, these results implicate NETs and the Act1 D</span>10N variant in human Th17 induction from peripheral blood mononuclear cells, with ramifications for immunogenetic studies of psoriasis and other autoimmune diseases. 30528823

2019

dbSNP: rs33980500
rs33980500
0.850 GeneticVariation BEFREE We have replicated the association of TRAF3IP2-_rs33980500 variant with the susceptibility to psoriasis. 24005976

2014

dbSNP: rs33980500
rs33980500
0.850 GeneticVariation BEFREE The hyperactive Th17 response combined with fully responsive fibroblasts likely synergized to contribute to psoriasis susceptibility in SNP-D10N patients. 25024377

2014

dbSNP: rs33980500
rs33980500
0.850 GeneticVariation BEFREE By contrast, healthy individuals homozygous for the common variant D10N, located in the ACT1 tumor necrosis factor receptor-associated factor-interacting domain and previously associated with psoriasis, had impaired, but not abolished, responses to IL-17 cytokines. 24120361

2013

dbSNP: rs33980500
rs33980500
0.850 GeneticVariation BEFREE In the absence of IL-17 signaling, IL-22 was the main contributor to skin inflammation, which provides a molecular mechanism for the association of Act1(D10N) with psoriasis susceptibility. 23202271

2013

dbSNP: rs33980500
rs33980500
T 0.850 GeneticVariation GWASCAT Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594

2012

dbSNP: rs33980500
rs33980500
0.850 GeneticVariation GWASDB Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594

2012

dbSNP: rs33980500
rs33980500
T 0.850 GeneticVariation GWASCAT Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. 20953188

2010

dbSNP: rs33980500
rs33980500
T 0.850 GeneticVariation GWASDB Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. 20953188

2010

dbSNP: rs7769061
rs7769061
G 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. 25903422

2015

dbSNP: rs13210247
rs13210247
0.700 GeneticVariation GWASDB Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. 20953188

2010

dbSNP: rs13196377
rs13196377
0.010 GeneticVariation BEFREE Minor allele of this SNP was always present in two haplotypes found to be associated with increased psoriasis risk: rs13196377_G + rs13190932_G + rs33980500_T + rs13210247_A (OR = 2.7, p = 0.0054) and rs13196377_A + rs13190932_A + rs33980500_T + rs13210247_G (OR = 1.8, p = 0.0008). 24005976

2014