Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3213094
rs3213094
0.800 GeneticVariation GWASDB A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190

2010

dbSNP: rs3213094
rs3213094
0.800 GeneticVariation GWASCAT A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190

2010

dbSNP: rs3213094
rs3213094
A 0.800 GeneticVariation GWASDB Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. 19169255

2009

dbSNP: rs3213094
rs3213094
A 0.800 GeneticVariation GWASCAT Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. 19169255

2009

dbSNP: rs2853694
rs2853694
G 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. 25903422

2015

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE Case-control analysis revealed an association of IL12B rs3212227 and IL23R rs11209026 minor allele carrier status with reduced odds for psoriasis (OR = 0.66, 95%CI: 0.50-0.87, and OR = 0.41, 95%CI: 0.26-0.67, respectively), while HLA-C*06 allele carriers were more frequent in patients group (OR = 4.56, 95%CI: 3.41-6.10). 29454820

2018

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE We found both SNPs were significantly associated with psoriasis</span> (rs7709212: odds ratio (OR)=1.37, P-value=1.09 × 10<sup>-5</sup>; rs321</span>2227: OR=1.38, P-value=8.88 × 10<sup>-6</sup>). 27829679

2017

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE Our results suggest that IL-12B (rs3212227) and IL-23R (rs2201841) polymorphisms confer increased risk of psoriasis in our ethnic South Indian Tamils. 26472011

2016

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE This study aims to assess whether the association between the non-susceptibility allelic variants of IL12B single-nucleotide polymorphism (SNPs) rs3212227 and rs6887695, IL23R SNPs rs11209026 and rs7530511, IL6 SNP rs1800795 and HLA-Cw6 could be correlated with decreased risk for psoriasis. 24140476

2014

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE This meta-analysis showed that the IL-23 R (rs11209026 and rs7530511) polymorphisms are associated with psoriasis risk in Europeans and that the IL-12B (rs6887695 and rs3212227) polymorphisms are associated with susceptibility to psoriasis in Europeans. 23844553

2013

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE For rs3212227, the odds ratios the minor allele for psoriasis and PsA were 0.688 (95 % CI 0.650-0.729) and 0.707 (95 % CI 0.628-0.797), respectively. 23297015

2013

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE Our study showed significant associations between psoriasis and both IL12B gene SNPs, rs3212227 (odds ratio (OR) = 1.35, P = 4.94E-04) and rs6887695 (OR = 1.32, P = 2.00E-03), but no significant association between psoriasis and the IL23R SNP, rs11209026. 23955419

2013

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE One of the IL12B markers, rs3212227, showed significant association with psoriasis (OR = 1.64, P = 0.0058) while the other, rs6887695, did not (OR = 1.29, P = 0.12). 19705136

2010

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE Both IL12B markers showed highly significant association with psoriasis in the case-control (rs3212227, odds ratio (OR)=1.62, P=1.7 x 10(-15); rs6887695, OR=1.49, P=2.7 x 10(-15)) and in the family-based analysis (rs3212227, P=2.2 x 10(-3); rs6887695, P=1.7 x 10(-3)). 18219280

2008

dbSNP: rs3212227
rs3212227
0.100 GeneticVariation BEFREE Haplotypes were estimated, and genotype-conditioned analyses identified a second risk allele (rs6887695) located approximately 60 kb upstream of the IL12B coding region that exhibited association with psoriasis after adjustment for rs3212227. 17236132

2007