rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
As BTNL2 (butyrophilin-like 2) gene polymorphism was found linked with the susceptibility to sarcoidosis, we investigated whether a specific genotype of BTNL2 gene G16071A (or rs2076530) single-nucleotide polymorphism (SNP) would be associated with the risk of sarcoid uveitis in all patient subgroups.
|
30872286 |
2019 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In the logistic regression models evaluating the association between HLA alleles and chronic sarcoidosis adjusted for rs1049550 and rs2076530, only DRB1*03 was significantly associated with disease resolution.
|
27662826 |
2018 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Host-genotype analysis revealed an association of the rs2076530 (<i>BTNL2</i>) risk allele with a decrease in bacterial burden (p=0.002).Our results indicate Scadding type-dependent microbiota in sarcoidosis BAL samples.<i>Atopobium</i> spp. and <i>Fusobacterium</i> spp. were identified as sarcoidosis-associated bacteria, which may enable new insights into the pathogenesis and treatment of the disease.
|
29242257 |
2017 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The sarcoidosis risk variant rs2076530 in BTNL2 was associated with all OFG (P = 0.013).
|
27306066 |
2016 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This meta-analysis indicates that BTNL2 rs2076530 polymorphism contributes to the risk of sarcoidosis.
|
25849037 |
2015 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We studied the polymorphism of the rs2076530 SNP of BTNL2 gene in 35 patients with sarcoidosis and cancer compared to 340 sarcoidosis without cancer, 271 controls and 32 cancer matched controls.
|
25078641 |
2014 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
GWASDB |
Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis.
|
22936702 |
2013 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis.
|
22936702 |
2013 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our data confirms the association of BTNL2 rs2076530 A allele with sarcoidosis susceptibility in a Portuguese population.
|
23017494 |
2012 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In our study, 11 single nucleotide polymorphisms (rs28362677, rs2076533, rs2076530, rs2076529, rs2294881, rs3763304, rs2076523, rs28362682, rs3806156, rs9268499, rs3763317), including the functional rs2076530 (G > A) of the BTNL2 gene, and HLA-DRB1 and -DQB1 alleles, were genotyped in 237 Japanese patients diagnosed with sarcoidosis and 287 healthy Japanese control subjects.
|
22991420 |
2012 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
An association has been reported between sarcoidosis and a single nucleotide polymorphism in BTNL2, rs2076530, also termed the A allele.
|
21410903 |
2011 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
But, no significant association was detected between any of the polymorphisms investigated and TB, including rs2076530 SNP that was previously found to be associated with sarcoidosis.
|
20176143 |
2010 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In summary, HLA-DRB1*14, DRB1*12, and BTNL2 haplotype 4--but not rs2076530 A--are associated with non-Löfgren sarcoidosis.
|
17661910 |
2007 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Significant differences were not demonstrable for the sarcoidosis associated splice-site variation (rs2076530 pallelic = 0.80) in our WG cohort.
|
16526951 |
2006 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Recent studies in sarcoidosis have identified association of a single nucleotide polymorphism (SNP) rs2076530 within BTNL2, a potential T-cell inhibitor, independent of the known DRB1 association.
|
16984233 |
2006 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Although rs2076530</span> was not associated with sarcoidosis in either African American sample, a three-locus haplotype that included rs2076530 was associated with sarcoidosis across all three study samples.
|
16080124 |
2005 |
rs479777
|
|
|
0.810 |
GeneticVariation |
GWASDB |
A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.
|
22837380 |
2012 |
rs479777
|
|
|
0.810 |
GeneticVariation |
BEFREE |
We identified chromosome 11q13.1 (rs479777) as a novel locus influencing susceptibility to sarcoidosis with genome-wide significance.
|
22837380 |
2012 |
rs479777
|
|
|
0.810 |
GeneticVariation |
GWASCAT |
A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.
|
22837380 |
2012 |
rs1964995
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.
|
26651848 |
2016 |
rs1953600
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis.
|
22936702 |
2013 |
rs1953600
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis.
|
22936702 |
2013 |
rs1964995
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
rs1953600
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In this population of Caucasian patients with sarcoidosis, only DRB1*03 was associated with disease resolution after 2 years' follow-up, with no significant interactions found for susceptibility gene SNPs ANXA11 rs1049550 or BTNL2 rs2076530.
|
27662826 |
2018 |