Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE These findings are the first to suggest an association between rs12807809 and abnormal Papez circuit function in patients with SZ. 30953482

2019

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE We observed an association of rs12807809 with SCZ in this study population. 28389239

2017

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE A meta-analysis of rs12807809 was also conducted to verify its association with schizophrenia in Han Chinese population. 26828755

2016

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE In conclusion rs12807809 polymorphism may not contribute to the risk of schizophrenia but influence the clinical symptoms of schizophrenia in the Han population. 25739323

2015

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE After applying Bonferroni correction for 13 genotype measures and setting P-values for significance (P<0.0039; 0.05/13), three effects remained significant: the rs12807809-rs12278912 diplotype-diagnosis interactions on performance intelligence quotient (CG/CG: P=3.9 × 10(-13); TA/TA: P=1.1 × 10(-7)) and TA/TA diplotype on performance intelligence quotient in patients with schizophrenia (P=8.2 × 10(-8)) remained significant. 23903071

2013

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE Effects of the neurogranin variant rs12807809 on thalamocortical morphology in schizophrenia. 24386483

2013

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE Two schizophrenia-associated NRGN SNPs (rs12807809 and rs12541) were tested for association with working memory-elicited dorsolateral prefrontal cortex (DLPFC) activity and surface-wide cortical thickness. 24098564

2013

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE Genetic variation in rs12807809 in the NRGN gene has recently been confirmed to be associated with schizophrenia in a meta-analysis of genome-wide association studies: the T-allele was found to be genome-wide significantly associated with schizophrenia. 21799211

2013

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE The effect of the neurogranin schizophrenia risk variant rs12807809 on brain structure and function. 22856365

2012

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE This study provides further evidence of the association of the NRGN gene with schizophrenia, and our results suggest that there is a link between the TG haplotype of rs12807809-rs12278912, decreased expression of NRGN and risk of developing schizophrenia. 22461181

2012

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE In order to find the causal variants of NRGN gene in schizophrenia, we searched for genetic variants in the promoter region and all the exons (including both UTR ends and rs12807809) using direct sequencing in a sample of patients with schizophrenia (n=346) and non-psychotic controls (n=345), both being Han Chinese from Taiwan, and conducted an association and functional study. 22306195

2012

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE Genotype effects of rs12807809 were investigated on gray matter (GM) and white matter (WM) volumes using magnetic resonance imaging (MRI) with a voxel-based morphometry (VBM) technique in a sample of 99 Japanese patients with schizophrenia and 263 healthy controls. 22253779

2012

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation GWASDB Common variants at VRK2 and TCF4 conferring risk of schizophrenia. 21791550

2011

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE We sought to determine if (a) NRGN contains common exonic variants or variants affecting expression (eQTLs) that could account for the association with rs12807809 and (b) there exist rare non-synonymous highly penetrant variants that could potentially confer high risk of schizophrenia. 21538840

2011

dbSNP: rs12807809
rs12807809
0.900 GeneticVariation BEFREE Our results confirm that common risk factors in the major histocompatibility complex region and TCF4 gene are associated with schizophrenia in Han Chinese, but our results fail to show an association with SNP rs12807809 in the NRGN gene. 20673877

2010

dbSNP: rs12807809
rs12807809
T 0.900 GeneticVariation GWASDB Common variants conferring risk of schizophrenia. 19571808

2009

dbSNP: rs12807809
rs12807809
T 0.900 GeneticVariation GWASCAT Common variants conferring risk of schizophrenia. 19571808

2009