|
rs187269
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We found that the allele G of rs187269 in the GABRB2 gene was significantly associated with better cognitive flexibility (P = 0.005), a major aspect of executive function, in patients with first episode schizophrenia.
|
30706170 |
2019 |
|
rs187269
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The findings showed no association between six single-nucleotide polymorphisms of GABRB2 (rs6556547, rs1816071, rs1816072, rs194072, rs252944, and rs187269) and SCZ in a total of 51,491 patients and 74,667 controls.
|
29894498 |
2018 |
|
rs187269
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Four single nucleotide polymorphisms (SNPs) in GABRB2, namely rs6556547 (S1), rs1816071 (S3), rs18016072 (S5), and rs187269 (S29), previously associated with schizophrenia, were examined for their association with heroin dependence.
|
26561861 |
2015 |
|
rs187269
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Disease-control differences were significantly correlated with SNP rs187269 in BPD males for both beta(2S1) and beta(2S2) expressions, and significantly correlated with SNPs rs2546620 and rs187269 in SCZ males for beta(2S2) expression.
|
19763268 |
2009 |
|
rs187269
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Using the multifactor-dimensionality reduction method (MDR), we found that the interactions among the rs187269C/T polymorphism in the GABRB2 gene, the -243A/G polymorphism in the GAD2 gene and the 27379C/T and 661C/T polymorphisms in the GAD1 gene revealed a significant association with schizophrenia (P<0.001).
|
17412563 |
2007 |
|
rs187269
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A converging body of evidence implicates the gamma-amino butyric acid neurotransmitter system in the pathogenesis of schizophrenia.Recently, Lo et al. reported strong positive association between schizophrenia and GABRB2, demonstrated by single markers and haplotypes of five markers in introns of GABRB2, rs6556547, rs1816071, rs194072, rs252944, and rs187269.
|
16023997 |
2005 |
|
rs187269
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Five SNPs in GABRB2, namely B2I7G1584T, rs1816071, rs194072, rs252944 and rs187269, were found to be significantly associated, and their haplotypes in linkage disequilibrium, with schizophrenia.
|
14699426 |
2004 |