Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2476601
rs2476601
0.760 GeneticVariation GWASCAT Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases. 30573655

2019

dbSNP: rs2476601
rs2476601
0.760 GeneticVariation BEFREE This meta-analysis confirms that the PTPN22 C1858T polymorphism is associated with SSc susceptibility and ACA status in Europeans, and that its prevalence is dependent on ethnicity. 21688149

2012

dbSNP: rs2476601
rs2476601
0.760 GeneticVariation BEFREE The PTPN22 C1858T variant as a risk factor for rheumatoid arthritis and systemic lupus erythematosus but not for systemic sclerosis in the Colombian population. 22704547

2012

dbSNP: rs2476601
rs2476601
0.760 GeneticVariation BEFREE The meta-analysis revealed evidence of association of the rs2476601 T allele with SSc susceptibility (p(FDRcorrected)=0.03 pooled, OR 1.15, 95% CI 1.03 to 1.28). 21131644

2011

dbSNP: rs2476601
rs2476601
0.760 GeneticVariation BEFREE We then conducted a meta-analysis of the most recent studies of SSc in order to verify the association or lack of association between the PTPN22 1858C>T variant and SSc. 18576360

2008

dbSNP: rs2476601
rs2476601
0.760 GeneticVariation BEFREE Lack of association of the PTPN22 gene polymorphism R620W with systemic sclerosis. 16870103

2006

dbSNP: rs2476601
rs2476601
0.760 GeneticVariation BEFREE The association of subsets of SSc with the PTPN22 R620W polymorphism further strengthens the classification of SSc within the spectrum of autoimmune diseases and strongly suggests the involvement of common susceptibility genes and similarly disordered immunoregulatory pathways. 17133608

2006