|
rs80359584
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs113488022
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not identify any tumours with the BRAF V600E mutation and transcriptome analysis revealed no significant differences between hypo- and hyper-methylated seminomas.
|
27886677 |
2016 |
|
rs121913377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not identify any tumours with the BRAF V600E mutation and transcriptome analysis revealed no significant differences between hypo- and hyper-methylated seminomas.
|
27886677 |
2016 |
|
rs3808350
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared to control population, loss of homozygous ancestral genotype GG in two polymorphisms located in the promoter region of GPER (rs3808350 and rs3808351) was more frequent in seminomas but not in non-seminomas (respectively, OR = 1.960 (1.172-3.277) and 7.000 (2.747-17.840); p < 0.01).
|
24451139 |
2014 |
|
rs3808351
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared to control population, loss of homozygous ancestral genotype GG in two polymorphisms located in the promoter region of GPER (rs3808350 and rs3808351) was more frequent in seminomas but not in non-seminomas (respectively, OR = 1.960 (1.172-3.277) and 7.000 (2.747-17.840); p < 0.01).
|
24451139 |
2014 |
|
rs34777958
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In humans we identified heterozygous germline LRRC50 mutations in two different pedigrees with a family history of seminomas, resulting in a nonsense Arg488* change and a missense Thr590Met change, which show reduced expression of the wild-type allele in seminomas.
|
23599692 |
2013 |
|
rs7371084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in ESR1 (rs9397080; OR=1.85, 95% CI: 1.18-2.91) and LHCGR (rs7371084; OR=2.37, 95% CI: 1.26-4.49) associated with risk of seminoma and metastasis, respectively.
|
22245602 |
2012 |
|
rs9397080
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in ESR1 (rs9397080; OR=1.85, 95% CI: 1.18-2.91) and LHCGR (rs7371084; OR=2.37, 95% CI: 1.26-4.49) associated with risk of seminoma and metastasis, respectively.
|
22245602 |
2012 |
|
rs1355972653
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analyses of haplotypes for LTA-TNF SNPs (LTA -91C>A, LTA 252A>G, TNF -863C>A, TNF -857C>T, TNF -308G>A, and -238G>A) were similarly suggestive of an association with TGCT (P = 0.06) and nonseminoma (P = 0.04), but not seminoma (P = 0.21).
|
17220333 |
2007 |
|
rs745738344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analyses of haplotypes for LTA-TNF SNPs (LTA -91C>A, LTA 252A>G, TNF -863C>A, TNF -857C>T, TNF -308G>A, and -238G>A) were similarly suggestive of an association with TGCT (P = 0.06) and nonseminoma (P = 0.04), but not seminoma (P = 0.21).
|
17220333 |
2007 |
|
rs1057519710
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel missense mutation (D816H) was found in the phosphotransferase domain in tumors of seminoma/dysgerminoma differentiation.
|
10362788 |
1999 |
|
rs121913506
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel missense mutation (D816H) was found in the phosphotransferase domain in tumors of seminoma/dysgerminoma differentiation.
|
10362788 |
1999 |