rs104893877
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Neuronal expression of familial Parkinson's disease A53T α-synuclein causes early motor impairment, reduced anxiety and potential sleep disturbances in mice.
|
23938351 |
2013 |
rs1057521223
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs1057521721
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability.
|
29016847 |
2017 |
rs1057524157
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
Functional analysis of novel DEAF1 variants identified through clinical exome sequencing expands DEAF1-associated neurodevelopmental disorder (DAND) phenotype.
|
28940898 |
2017 |
rs1057524157
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
Exome analysis of Smith-Magenis-like syndrome cohort identifies de novo likely pathogenic variants.
|
28213671 |
2017 |
rs1057524820
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs1060499733
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1064793575
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs10766075
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).
|
24673294 |
2014 |
rs10830963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings do not support participation of the MTNR1B gene variant rs10830963 in the well documented association between sleep disturbances and type 2 diabetes.
|
21380592 |
2011 |
rs1085307845
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs10864315
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The main positive findings refer to associations between selected polymorphisms and: 1) chronotype with the ARNTL gene (rs11824092 and rs1481892) and the CLOCK (rs1268271) 2) sleep duration with the CLOCK gene (rs3805148) and the TIM gene (rs2291739) 3) daytime dysfunction with the PER3 gene (rs228727, rs228642, rs10864315) 4) subjective sleep quality with the ARNTL gene (rs11824092, rs1982350) 5) sleep disturbances with the ARNTL gene (rs11600996) We also found the significant epistatic interactions between polymorphism of the PER3 gene (rs2640909) & the CLOCK gene (rs11932595) and following sleep quality variables: sleep duration, habitual sleep efficiency and subjective sleep quality.
|
27102916 |
2016 |
rs11022778
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).
|
24673294 |
2014 |
rs1131692231
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1135401778
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Haploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features.
|
28942966 |
2017 |
rs11600996
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The main positive findings refer to associations between selected polymorphisms and: 1) chronotype with the ARNTL gene (rs11824092 and rs1481892) and the CLOCK (rs1268271) 2) sleep duration with the CLOCK gene (rs3805148) and the TIM gene (rs2291739) 3) daytime dysfunction with the PER3 gene (rs228727, rs228642, rs10864315) 4) subjective sleep quality with the ARNTL gene (rs11824092, rs1982350) 5) sleep disturbances with the ARNTL gene (rs11600996) We also found the significant epistatic interactions between polymorphism of the PER3 gene (rs2640909) & the CLOCK gene (rs11932595) and following sleep quality variables: sleep duration, habitual sleep efficiency and subjective sleep quality.
|
27102916 |
2016 |
rs11824092
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The main positive findings refer to associations between selected polymorphisms and: 1) chronotype with the ARNTL gene (rs11824092 and rs1481892) and the CLOCK (rs1268271) 2) sleep duration with the CLOCK gene (rs3805148) and the TIM gene (rs2291739) 3) daytime dysfunction with the PER3 gene (rs228727, rs228642, rs10864315) 4) subjective sleep quality with the ARNTL gene (rs11824092, rs1982350) 5) sleep disturbances with the ARNTL gene (rs11600996) We also found the significant epistatic interactions between polymorphism of the PER3 gene (rs2640909) & the CLOCK gene (rs11932595) and following sleep quality variables: sleep duration, habitual sleep efficiency and subjective sleep quality.
|
27102916 |
2016 |
rs11824092
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).
|
24673294 |
2014 |
rs11932595
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The main positive findings refer to associations between selected polymorphisms and: 1) chronotype with the ARNTL gene (rs11824092 and rs1481892) and the CLOCK (rs1268271) 2) sleep duration with the CLOCK gene (rs3805148) and the TIM gene (rs2291739) 3) daytime dysfunction with the PER3 gene (rs228727, rs228642, rs10864315) 4) subjective sleep quality with the ARNTL gene (rs11824092, rs1982350) 5) sleep disturbances with the ARNTL gene (rs11600996) We also found the significant epistatic interactions between polymorphism of the PER3 gene (rs2640909) & the CLOCK gene (rs11932595) and following sleep quality variables: sleep duration, habitual sleep efficiency and subjective sleep quality.
|
27102916 |
2016 |
rs11932595
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).
|
24673294 |
2014 |
rs1212171
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype at the NTRK2 SNP rs1212171 was associated with both sleep disturbance and fatigue.
|
28205449 |
2017 |
rs1229030855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six missense changes were detected only in individuals with ASD with sleep disturbance: p.F498S in TIMELESS, p.S20R in NR1D1, p.R493C in PER3, p.H542R in CLOCK, p.L473S in ARNTL2, and p.A325V in MTNR1B.
|
25957987 |
2016 |
rs1380822792
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs142110773
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs1448259271
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|