The case-control study revealed an association between another IL1A variant (rs1894399) and AS(p=0.035), and between IL1F10.3 (rs3811058) and spondyloarthritis (p=0.041).
In addition to the three known IL-1 polymorphisms, rs2856836, rs17561, and rs1894399, found in previous meta-analysis, this meta-analysis shows that the IL-1F10.3 and IL-1A+889 polymorphisms are associated with the development of AS in Europeans but not in Asians.