Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE No significant difference was found between the AS susceptibility and polymorphisms of rs27044 and rs27434. 30461632

2018

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE Our results indicated a difference in the mechanism of susceptibility loci in subsets of Zhejiang Han Chinese population and provided further evidence that rs27434 is the key polymorphism associated with AS in ERAP1 gene. 26350268

2016

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE ERAP1 gene rs27434 and rs7711564 polymorphisms may increase the risk of AS. 26617903

2015

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE Our study also confirmed a weak association between ERAP1 (rs27434) and AS. 24666027

2014

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE Except in rs27434 (P = 0.23), the significant correlation between ERAP1 polymorphisms and AS susceptibility has been detected in rs27044 (OR 1.57, P < 0.001), rs17482078 (OR 1.271, P < 0.001), rs10050860 (OR 0.772, P = 0.006), rs30187 (OR 1.348, P < 0.001), rs2287987 (OR 0.746, P < 0.001) and rs27037 (OR 1.257, P = 0.001). 21229357

2012

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE Two specific haplotypes including: rs30187/ rs469876/ rs13167972/ rs27434 TAAA and CAGG were associated with increased and decreased risk of AS in Iranian population, respectively. 23264405

2012

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE This is the first confirmation in a nonwhite population that genetic polymorphisms of rs27037, rs27434, and rs10865331 are associated with AS, implicating common pathogenetic mechanisms in Korean and white patients with AS. 21041274

2011

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE Two SNP (rs27434, p = 0.00039, and rs27529, p = 0.0083) in ERAP1 other than that reported previously were found to be significantly associated with AS. 21078719

2011

dbSNP: rs27434
rs27434
A 0.890 GeneticVariation GWASCAT Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. 20062062

2010

dbSNP: rs27434
rs27434
A 0.890 GeneticVariation GWASDB Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. 20062062

2010

dbSNP: rs27434
rs27434
0.890 GeneticVariation BEFREE We report several new associations between AS and polymorphisms distributed across ERAP1 from the extended case-control study, the most significant of which was with rs27434 (P = 4.7 x 10(-7)). 19692350

2009