| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | BEFREE | Although our nominally significant results did not withstand correction for multiple tests they may support a relevance of the COMT (Val158Met) and IL6 rs1800795 polymorphism for aspects of PTSD in war traumatized individuals. | 31291232 | 2019 |
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|
0.080 | GeneticVariation | BEFREE | Genetic pathways to posttraumatic stress disorder and depression in children: Investigation of catechol-O-methyltransferase (COMT) Val158Met using different PTSD diagnostic models. | 29627597 | 2018 |
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|
0.080 | GeneticVariation | BEFREE | COMT val158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma. | 28833952 | 2018 |
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|
0.080 | GeneticVariation | BEFREE | Hierarchical linear regression was used to model the genotype (Val158Met polymorphism) × PTSD severity interaction and its association with hippocampal volume. | 28234210 | 2017 |
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|
0.080 | GeneticVariation | BEFREE | The 3'-UTR variable number tandem repeat (VNTR) in SLC6A3 also showed significant association with PTSD (OR = 1.62, 95% CI: 1.12-2.35; P = 0.010), but there was no association of rs4680 in COMT with PTSD (P = 0.595). | 26986136 | 2016 |
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|
0.080 | GeneticVariation | BEFREE | The present study sought to replicate previous findings of an association between the Catechol-O-methyltransferase (COMT) val158met polymorphism with posttraumatic stress disorder (PTSD) and symptomatology in a novel age group, preschool children. | 25329975 | 2014 |
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|
0.080 | GeneticVariation | BEFREE | Our findings suggest Val158Met genotype moderates the effect of PTSD-related processes on right ACC volume. | 21783175 | 2011 |
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|
0.080 | GeneticVariation | BEFREE | The present findings indicate a gene-environment interaction between the human COMT Val158Met polymorphism and the number of traumatic event types experienced in the risk of developing PTSD. | 19944409 | 2010 |