DisGeNET - a database of gene-disease associations

Post-Traumatic Stress Disorder, C0038436

Variant: rs8042149 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs8042149

RORA

0.720

GeneticVariation

BEFREE

No significant results were observed for OXTR rs2254298, RORA rs8042149 and CNR1 rs1049353 although the results for RORA showed a slight tendency that rs8042149 may influence the level of BSI scores in current PTSD patients.

31291229

2019

dbSNP:

rs8042149

RORA

0.720

GeneticVariation

BEFREE

Our results showed that the interaction of rs8042149 genotype x trauma exposure was associated with total PTSD symptoms in males.

28262136

2017

dbSNP:

rs8042149

RORA

0.720

GeneticVariation

GWASDB

A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.

22869035

2013