<i>Results:</i> Polymorphism in <i>XRCC1</i> rs25487 was significantly associated with reduced ischemic stroke (IS) risk (dominant model: OR = 0.53, 95% CI = 0.36-0.79, <i>p</i> = 0.002), a milder initial stroke (dominant model: OR = 0.57, 95% CI = 0.33-0.98, <i>p</i> = 0.043), and also a better short-term recovery (dominant model: OR = 0.57, 95% CI = 0.35-0.92, <i>p</i> = 0.022).
Genotyping of polymorphisms of the OGG1 (Ser326Cys), XRCC1 (Arg399Gln), ERCC2 (Lys751Gln), and ERCC5 (Asp1104His) genes was performed and used to evaluate LAA stroke susceptibility.