|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
rs11190870 in LBX1, a strong susceptibility SNP for AIS, may also be a susceptibility SNP for ASD.
|
31365516 |
2019 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The pooled results showed a statistically significant association between LBX1 gene polymorphisms and AIS (for rs11190870, T vs C, OR = 1.54, 95% CI = 1.48-1.61, P < .00001; for rs625039, G vs A, OR = 1.50, 95% CI: 1.38-1.62; P < .00001; for rs678741, G vs A, OR = 0.74, 95% CI: 0.63-0.86; P < .0001; for rs11598564, G vs A, OR = 1.41, 95% CI: 1.31-1.51; P < .0001).
|
31277174 |
2019 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We evaluated the association between rs11190870 and AIS progression for the entire group, and then for patients grouped according to a severe curve (a Cobb angle of ≥40°) or mild curve (a Cobb angle <30°).
|
28902104 |
2018 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A significant association of rs11190870 with AIS was observed in multiple ethnic groups regardless of gender.
|
29535018 |
2018 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Four markers showed association with AIS in our cohort at this locus; rs11190870 the most studied marker, rs7893223, rs594791, and rs11190878.
|
28604496 |
2018 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two SNPs around LBX1, rs11190870 and rs1322331 are associated with AIS in northern Chinese Han population.
|
28187071 |
2017 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We found rs11190870, downstream of LBX1 and previously associated with AIS in Asian populations, to be in modest linkage disequilibrium (LD) with rs11190878 (r(2) = 0.40, D' = 0.81).
|
25675428 |
2015 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Based on a comprehensive analysis of the currently available evidence, rs11190870 is likely a susceptibility variant for AIS in East Asians.
|
24878781 |
2014 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The SNP rs11190870 near LBX1 is associated with both susceptibility and curve progression of AIS.
|
23096252 |
2013 |
|
rs11190870
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recently, a genome-wide association study (GWAS) in a Japanese population indicated that three single nucleotide polymorphisms (SNPs), rs11190870, rs625039 and rs11598564, all located near the LBX1 gene, may be associated with AIS susceptibility [1].
|
23308168 |
2013 |