<i>GSTP1</i> rs1695 showed the smallest p value for hematotoxicity association, and the <sup>105</sup>Ile wild type allele had a significantly higher risk of severe hematotoxicity (neutropenia G4, thrombocytopenia ≥ G3 and anemia ≥ G3) than the <sup>105</sup>Val allele (p=0.00034, odds ratio=5.71 (95% confidence interval:1.77-18.44)).
The aim of the study is to evaluate the association between granulocytopenia and thrombocytopenia induced by platinum-based drugs and GSTP1 rs1695 gene polymorphism by meta-analysis.