Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs727503094
rs727503094
HRAS ; LRRC56
0.010 GeneticVariation BEFREE One thymoma and one thymic carcinoma harbored KRAS mutations (G12A and G12V, respectively), and one thymoma had a G13V HRAS mutation. 19861435

2009
dbSNP: rs104894226
rs104894226
HRAS ; LRRC56
0.710 GeneticVariation BEFREE One thymoma and one thymic carcinoma harbored KRAS mutations (G12A and G12V, respectively), and one thymoma had a G13V HRAS mutation. 19861435

2009
dbSNP: rs112445441
rs112445441
KRAS
0.010 GeneticVariation BEFREE One thymoma and one thymic carcinoma harbored KRAS mutations (G12A and G12V, respectively), and one thymoma had a G13V HRAS mutation. 19861435

2009
dbSNP: rs1131692239
rs1131692239
KIT
T 0.700 CausalMutation CLINVAR Promising efficacy of sorafenib in a relapsed thymic carcinoma with C-KIT exon 11 deletion mutation. 20970876

2011
dbSNP: rs104894226
rs104894226
HRAS ; LRRC56
A 0.710 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs1057519711
rs1057519711
KIT
A 0.700 CausalMutation CLINVAR Sorafenib inhibits the imatinib-resistant KITT670I gatekeeper mutation in gastrointestinal stromal tumor. 17699867

2007
dbSNP: rs121434569
rs121434569
EGFR ; EGFR-AS1
0.010 GeneticVariation BEFREE The PC-9-derived NSCLC cell lines PC-9ER and PC-9ZD, resistant to EGFR-TKI due to v-crk avian sarcoma virus CT10 oncogene homolog-like (CRKL) amplification-induced phosphatidylinositol 3-kinase (PI3K)/v-akt murine thymoma viral oncogene homolog (AKT) activation and an EGFR T790M mutation, respectively, were used. 24698130

2014
dbSNP: rs77375493
rs77375493
JAK2 ; INSL6
0.010 GeneticVariation BEFREE This activity was coupled with inhibition of phosphorylation of the key JAK2(V617F)-dependent downstream signaling effectors signal transducer and activator of transcription (STAT)3, STAT5, and v-akt murine thymoma viral oncogene homolog (AKT). 18482053

2008
dbSNP: rs121913685
rs121913685
KIT
G 0.700 CausalMutation CLINVAR Thymic carcinoma with overexpression of mutated KIT and the response to imatinib. 15201427

2004
dbSNP: rs104894226
rs104894226
HRAS ; LRRC56
A 0.710 GeneticVariation CLINVAR Thymic tumors: relevant molecular data in the clinic. 20859122

2010