rs74799832
|
|
|
0.720 |
GeneticVariation |
BEFREE |
In the present study, we investigated whether the oncogenic RET mutants RET2A (C634R) and RET2B (M918T) were regulated by LRIG1, and the possible effects of LRIG1 expression in thyroid cancer were investigated in three different clinical cohorts and in a RET2B-driven mouse model of MTC.
|
29436694 |
2018 |
rs74799832
|
|
|
0.720 |
GeneticVariation |
BEFREE |
In present result, RET rs1799939, rs1800858 and rs74799832 polymorphisms might be the risk factors for TC.
|
26191299 |
2015 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial.
|
22025146 |
2012 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Thyroid cancer cell lines harboring RET/PTC1 (TPC-1), RET M918T (MZ-CRC1) and RET C634W (TT) alterations, as well as TPC-1 xenografts, were treated with JAK inhibitor, AZD1480.
|
23056499 |
2012 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Targeted therapies for thyroid tumors.
|
21455200 |
2011 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
The effects of four different tyrosine kinase inhibitors on medullary and papillary thyroid cancer cells.
|
21470995 |
2011 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation.
|
20847059 |
2010 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer.
|
20065189 |
2010 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer.
|
20368568 |
2010 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Phase II trial of sorafenib in metastatic thyroid cancer.
|
19255327 |
2009 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Phase II trial of sorafenib in advanced thyroid cancer.
|
18541894 |
2008 |
rs74799832
|
|
C |
0.720 |
CausalMutation |
CLINVAR |
Molecular biology of the MEN2 gene.
|
9681850 |
1998 |