Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE (2) In subgroup analysis based on ethnicity, TLR2 Arg753Gln</span> polymorphism elevates the risk of TB in Asian and Caucasian populations, but not in African or mixed populations. 30733958

2019

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE In conclusion, the present data suggest that the arginine to glutamine substitution at residue 753 polymorphism of the Toll-like receptor 2 gene influences the risk of developing tuberculosis. 14979495

2004

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE Our data suggest that the Arg753Gln polymorphism of the TLR-2 gene influences the speed of progression from infection to TB disease in children. 21320563

2011

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE Our meta-analysis provides evidence that the TLR2 gene Arg753Gln polymorphism is a risk factor to TB, especially in Asian populations. 26220088

2015

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE Polymorphisms of the toll-like receptor 2 (TLR2) gene (Arg677Trp, Arg753Gln) and the TLR4 gene (Asp299Gly, Thr399Ile) were investigated in 205 tuberculosis (TB) patients and 203 controls. 20002809

2010

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE The rs5743708 gene polymorphism in the TLR2 gene contributes to the risk of tuberculosis disease</span>. 26617949

2015

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE The R753Q TLR2 polymorphism has been associated with increased incidence of tuberculosis and infections with non-tuberculous mycobacteria in human populations, but the mechanisms by which this polymorphism affects TLR2 signaling are unclear. 28442574

2017

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE The meta-analysis indicated that TLR2 G2258A is associated with increased TB risk, especially in Asians and Europeans. 23691034

2013

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE This case-control study aims to determine the influence of TLR2 (Arg753Gln and Arg677Trp) polymorphisms on the susceptibility to develop pulmonary or peritoneal TB. 28332241

2017

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE TLR2 rs5743708 subgroup analysis identified the A allele to increase susceptibility to TB in the Asian ethnic group, while conferring protection in the Hispanic group. 26430737

2015

dbSNP: rs5743708
rs5743708
0.100 GeneticVariation BEFREE We also detected an association of TLR2 gene with tuberculosis (rs5743708; 3.19 [2.03-5.02]). 26524966

2015