rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
(2) In subgroup analysis based on ethnicity, TLR2 Arg753Gln</span> polymorphism elevates the risk of TB in Asian and Caucasian populations, but not in African or mixed populations.
|
30733958 |
2019 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The R753Q TLR2 polymorphism has been associated with increased incidence of tuberculosis and infections with non-tuberculous mycobacteria in human populations, but the mechanisms by which this polymorphism affects TLR2 signaling are unclear.
|
28442574 |
2017 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This case-control study aims to determine the influence of TLR2 (Arg753Gln and Arg677Trp) polymorphisms on the susceptibility to develop pulmonary or peritoneal TB.
|
28332241 |
2017 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We also detected an association of TLR2 gene with tuberculosis (rs5743708; 3.19 [2.03-5.02]).
|
26524966 |
2015 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The rs5743708 gene polymorphism in the TLR2 gene contributes to the risk of tuberculosis disease</span>.
|
26617949 |
2015 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our meta-analysis provides evidence that the TLR2 gene Arg753Gln polymorphism is a risk factor to TB, especially in Asian populations.
|
26220088 |
2015 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
TLR2 rs5743708 subgroup analysis identified the A allele to increase susceptibility to TB in the Asian ethnic group, while conferring protection in the Hispanic group.
|
26430737 |
2015 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The meta-analysis indicated that TLR2 G2258A is associated with increased TB risk, especially in Asians and Europeans.
|
23691034 |
2013 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our data suggest that the Arg753Gln polymorphism of the TLR-2 gene influences the speed of progression from infection to TB disease in children.
|
21320563 |
2011 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphisms of the toll-like receptor 2 (TLR2) gene (Arg677Trp, Arg753Gln) and the TLR4 gene (Asp299Gly, Thr399Ile) were investigated in 205 tuberculosis (TB) patients and 203 controls.
|
20002809 |
2010 |
rs5743708
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, the present data suggest that the arginine to glutamine substitution at residue 753 polymorphism of the Toll-like receptor 2 gene influences the risk of developing tuberculosis.
|
14979495 |
2004 |