Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs387906735
rs387906735
TRNF
G 0.700 CausalMutation CLINVAR

dbSNP: rs2222202
rs2222202
IL10 ; IL19
0.010 GeneticVariation BEFREE The homozygous minor allele in IL-10 +434T (rs2222202) and IL-10+504G (rs3024490) was found in all patients with TIN or TINU syndrome while the frequency of these minor alleles in the control population was 44% and 23%, respectively (p <0.001). 30779760

2019
dbSNP: rs3024490
rs3024490
IL10 ; IL19
0.010 GeneticVariation BEFREE The homozygous minor allele in IL-10 +434T (rs2222202) and IL-10+504G (rs3024490) was found in all patients with TIN or TINU syndrome while the frequency of these minor alleles in the control population was 44% and 23%, respectively (p <0.001). 30779760

2019
dbSNP: rs140511594
rs140511594
TTC21B ; TTC21B-AS1
0.010 GeneticVariation BEFREE Our results confirm the causal role of the homozygous p.P209L TTC21B mutation in two new families with FSGS and tubulointerstitial disease. 26940125

2017
dbSNP: rs360719
rs360719
IL18 ; TEX12 ; LOC107987164
0.010 GeneticVariation BEFREE IL18 rs360719 is probably associated with the pathogenesis of chronic infective tubulointerstitial nephritis. 25587543

2014
dbSNP: rs7903146
rs7903146
TCF7L2
0.010 GeneticVariation BEFREE This study found no association between rs7903146 polymorphism in the TCF7L2 gene and the increased risk for development of CKD caused by primary glomerulopathy and analysed tubulointerstitial nephropathy. 24864085

2014