Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.060 GeneticVariation BEFREE However, individuals with the T+ allele of r</span>s5443 (CT, TT) were susceptible to MD when exposed to low negative life events. 28225778

2017
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.060 GeneticVariation BEFREE Influence of GNB3 C825T polymorphism on the efficacy of antidepressants in the treatment of major depressive disorder: A meta-analysis. 25451402

2015
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.060 GeneticVariation BEFREE In the present study, we aimed to confirm the previous finding of an association between GRIK4 and GNB3 variants (rs195478 and rs5443) and remission and treatment resistance in major depression, using a multicenter sample of 223 patients. 22222462

2012
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.060 GeneticVariation BEFREE The result suggests that C825T variants of GNB3 cannot play a major role as a predictor of treatment response as well as intolerance to SSRIs in Japanese patients with major depression. 18325652

2008
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.060 GeneticVariation BEFREE These findings, taken together with other studies suggesting an influence of the C825T polymorphism in major depressive disorder, support the hypothesis of the involvement of G-proteins in mood regulation. 16897596

2007
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.060 GeneticVariation BEFREE Relationship between G-protein beta-3 subunit C825T polymorphism and mirtazapine responses in Korean patients with major depression. 17943025

2007