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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression.
|
31721892 |
2019 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of BDNF Val66Met Polymorphism and Brain BDNF Levels with Major Depression and Suicide.
|
29432620 |
2018 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The effects of 5-HTTLPR and BDNF Val66Met polymorphisms on neurostructural changes in major depressive disorder.
|
29414128 |
2018 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Val66Met polymorphism association with serum BDNF and inflammatory biomarkers in major depression.
|
28656803 |
2018 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients.
|
28848102 |
2017 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Effects of polymorphisms of serotonin transporter promoter (5-HTTLPR) and brain derived neurotrophic factor gene (G196A rs6265) on the risk of major depressive disorder in the Chinese Han population.
|
27212180 |
2016 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our study aimed to clarify whether, in the presence of previous childhood maltreatment, individuals carrying low functional alleles for both SERT 5-HTTLPR and BDNF Val66Met polymorphisms had a higher risk for MD.
|
25510949 |
2015 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder.
|
25745134 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This is a systematic meta-analytical review of findings from imaging genetic studies on the impact of the rs6265 SNP on hippocampal volumes in neuropsychiatric patients with major depressive disorder, anxiety, bipolar disorder or schizophrenia.
|
25956254 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The current study looked at a population of patients with major depressive disorder (N = 107) to examine the association between the BDNF Val66Met polymorphism, resting state EEG alpha power, and depression severity.
|
23733090 |
2013 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Common genetic variants, such as the brain-derived neurotrophic factor (BDNF) Val/66/Met polymorphism (rs6265), are known to interact with environmental factors such as early adversity to increase the risk of subsequent major depression.
|
22844024 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent meta-analyses point towards a pathogenic role of the Val66Met variant of the brain-derived neurotrophic factor (BDNF) in major depressive disorder, specifically in males.
|
22033217 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We found no significant association of either the BDNF G196A or MTHFR C677T polymorphisms with major depressive disorder neither in female nor male group of patients.
|
23255668 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated an association between the polymorphism of brain-derived neurotrophic factor (BDNF) gene Val66Met and the response to mirtazapine in Japanese patients with major depressive disorder (MDD).
|
22883353 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Reduced fractional anisotropy in the uncinate fasciculus in patients with major depression carrying the met-allele of the Val66Met brain-derived neurotrophic factor genotype.
|
22585743 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the current study, we examined BDNF polymorphisms (G-712A, C270T and Val66Met) in 202 patients with MD and 323 patients with schizophrenia.
|
21129438 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression.
|
21692988 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Hippocampal volumes and the brain-derived neurotrophic factor val66met polymorphism in geriatric major depression.
|
21218562 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the relationship between a brain-derived neurotrophic factor (BDNF) polymorphism (Val66Met) and the clinical response of patients with major depressive disorder to selective serotonin reuptake inhibitors (SSRIs; here, paroxetine and sertraline).
|
21338649 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity.
|
18852698 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder.
|
20167454 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Brain derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder.
|
20674983 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To conclude, we did not replicate the Val66Met effect on hippocampal volume in neither patients with major depression nor in healthy participants.
|
19668114 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To examine the effect of the BDNF Val66Met polymorphism on hippocampal and amygdala volumes in patients with major depression and in healthy control subjects.
|
17404118 |
2007 |