Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE It remains unclear whether B cell lymphomas with MYD88 L265P mutation respond differently toward CD8<sup>+</sup> T cell-mediated cytotoxicity. 30253331

2018

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE The importance of Myd88 L265P mutation, clinical and immunohistochemical prognostic factors for the survival of patients with diffuse large B-cell non-Hodgkin lymphoma treated by immunochemotherapy in southeast Serbia. 27837631

2017

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE 9/20 other B-cell lymphomas with identical light chain restriction on B-cells and plasma cells were genotypically identical by PCR and MYD88 L265P was detected in both cell fractions in 7/9 whereas in 11/20 specimens with different clonal origin, MYD88 L265P was absent (5/11), or only found in B-lymphocytes (4/11), or plasma cells (2/11). 27890075

2016

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE Thirty-three low-grade B-cell lymphomas with plasmacytic differentiation (23 MYD88(L265P) and 10 MYD88(WT)) involving various samples types (fresh and formalin-fixed tissues) formed the study group. 27268124

2016

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE In conclusion the detection of MYD88 L265P mutation in FFPE samples is reliable and useful for subtyping small B-cell lymphomas in BM biopsies. 25819228

2015

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE To assess the diagnostic utility of MYD88 L265P mutation in diagnosing low-grade B-cell lymphomas. 26230596

2015

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE Although not entirely specific, MYD88 L265P is a useful adjunct for bone marrow diagnosis in separating LPL from other small B-cell lymphomas and plasma cell myeloma. 23955458

2013

dbSNP: rs113488022
rs113488022
0.030 GeneticVariation BEFREE BRAF-V600E is the key driver mutation in HCL and distinguishes it from other B-cell lymphomas, including HCL-like leukemias/lymphomas (HCL-variant and splenic marginal zone lymphoma). 25480661

2015

dbSNP: rs113488022
rs113488022
0.030 GeneticVariation BEFREE Immunohistochemistry for BRAF V600E in the Differential Diagnosis of Hairy Cell Leukemia vs Other Splenic B-Cell Lymphomas. 26071465

2015

dbSNP: rs121913377
rs121913377
0.030 GeneticVariation BEFREE Immunohistochemistry for BRAF V600E in the Differential Diagnosis of Hairy Cell Leukemia vs Other Splenic B-Cell Lymphomas. 26071465

2015

dbSNP: rs121913377
rs121913377
0.030 GeneticVariation BEFREE BRAF-V600E is the key driver mutation in HCL and distinguishes it from other B-cell lymphomas, including HCL-like leukemias/lymphomas (HCL-variant and splenic marginal zone lymphoma). 25480661

2015

dbSNP: rs113488022
rs113488022
0.030 GeneticVariation BEFREE Here, we confirm the specificity of BRAF V600E for HCL among low and intermediate grade B-NHL and describe a real-time polymerase chain reaction method for detecting this mutation in cases with low tumour burden. 22246856

2012

dbSNP: rs121913377
rs121913377
0.030 GeneticVariation BEFREE Here, we confirm the specificity of BRAF V600E for HCL among low and intermediate grade B-NHL and describe a real-time polymerase chain reaction method for detecting this mutation in cases with low tumour burden. 22246856

2012

dbSNP: rs17757541
rs17757541
0.020 GeneticVariation BEFREE B-cell lymphoma 2 rs17757541 C>G polymorphism was associated with an increased risk of coronary artery disease in a Chinese population. 26823859

2015

dbSNP: rs17757541
rs17757541
0.020 GeneticVariation BEFREE B-cell Lymphoma 2 rs17757541 C>G polymorphism was associated with an increased risk of gastric cardiac adenocarcinoma in a Chinese population. 23991993

2013

dbSNP: rs1800629
rs1800629
TNF
0.020 GeneticVariation BEFREE TNF rs1800629, which was genotyped in only two of our studies, was also associated with B cell lymphoma (per-allele OR = 0.77, 95 % CI 0.64-0.91; p trend = 0.003), specifically DLBCL (per-allele OR = 0.69, 95 % CI 0.55-0.86; p trend = 0.001). 23640160

2013

dbSNP: rs1800629
rs1800629
TNF
0.020 GeneticVariation BEFREE Statistically significant interactions with blood transfusion were observed for IL10RA (rs9610) (P(forinteraction) = 0.003) and TNF (rs1800629) (P(forinteraction) = 0.012) for NHL overall and IL10RA (rs9610) (P(forinteraction) = 0.001) and TNF (rs1800629) (P(forinteraction) = 0.019) for B-cell lymphoma. 22649007

2012

dbSNP: rs121912438
rs121912438
0.010 GeneticVariation BEFREE RESULTS Ovariectomy advanced the onset of disease, down-regulated aromatase and estrogen receptor alpha (ER-a) expression, and inhibited expression of the anti-inflammatory factors arginase-1 and the anti-apoptotic factor B-cell lymphoma-2 (Bcl-2) in the lumbar spinal cord of hSOD1-G93A transgenic mice. 29394243

2018

dbSNP: rs2230926
rs2230926
0.010 GeneticVariation BEFREE A coding <i>TNFAIP3</i> variant, namely rs2230926, has been previously linked to B cell non-Hodgkin's lymphoma (NHL) development in patients with Sjogren's syndrome (SS) of French and UK origin. 30662920

2018

dbSNP: rs11886868
rs11886868
0.010 GeneticVariation BEFREE We investigated the association between B-cell lymphoma/leukaemia 11A (BCL11A) rs11886868 and rs4671393 polymorphism, plasma BCL11A concentration, and the hazard of developing laryngeal squamous cell carcinoma (LSCC). 28225775

2017

dbSNP: rs1472503583
rs1472503583
0.010 GeneticVariation BEFREE The importance of Myd88 L265P mutation, clinical and immunohistochemical prognostic factors for the survival of patients with diffuse large B-cell non-Hodgkin lymphoma treated by immunochemotherapy in southeast Serbia. 27837631

2017

dbSNP: rs4671393
rs4671393
0.010 GeneticVariation BEFREE We investigated the association between B-cell lymphoma/leukaemia 11A (BCL11A) rs11886868 and rs4671393 polymorphism, plasma BCL11A concentration, and the hazard of developing laryngeal squamous cell carcinoma (LSCC). 28225775

2017

dbSNP: rs1057520009
rs1057520009
0.010 GeneticVariation BEFREE In this retrospective study, we analyzed the recurrent hotspot mutation of the exportin 1 (XPO1, p.E571K) gene, previously identified in primary mediastinal B-cell lymphoma, in biopsies and plasma circulating cell-free DNA from patients with classical Hodgkin lymphoma using a highly sensitive digital PCR technique. 27479820

2016

dbSNP: rs539846
rs539846
BMF
0.010 GeneticVariation BEFREE SNP rs539846 C>A, the most highly associated variant (p = 1.42 × 10(-13), odds ratio = 1.35), localizes to a super-enhancer defined by extensive histone H3 lysine 27 acetylation in intron 3 of B cell lymphoma 2 (BCL2)-modifying factor (BMF). 27524613

2016

dbSNP: rs17655
rs17655
0.010 GeneticVariation BEFREE ERCC5 Asp1104His polymorphism showed a protective effect against the B-NHL in individuals carrying this mutant allele (p = 0.009), and differences were more prominent in males (p = 0.001). 25400036

2015