| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
A | 0.700 | CausalMutation | CLINVAR | Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study. | 27501770 | 2016 |
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|
A | 0.700 | CausalMutation | CLINVAR | Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol. | 26787237 | 2016 |
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|
A | 0.700 | CausalMutation | CLINVAR | High frequency of germline TP53 mutations in a prospective adult-onset sarcoma cohort. | 23894400 | 2013 |
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|
A | 0.700 | CausalMutation | CLINVAR | Gastric cancer in individuals with Li-Fraumeni syndrome. | 21552135 | 2011 |
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|
A | 0.700 | CausalMutation | CLINVAR | TP53 germline mutations in Portugal and genetic modifiers of age at cancer onset. | 19468865 | 2009 |
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|
A | 0.700 | CausalMutation | CLINVAR | Telomere length in peripheral blood cells of germline TP53 mutation carriers is shorter than that of normal individuals of corresponding age. | 17567834 | 2007 |
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|
A | 0.700 | CausalMutation | CLINVAR | Identification of novel TP53 mutations in familial and sporadic cancer cases of German and Swiss origin. | 15381368 | 2004 |
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|
A | 0.700 | CausalMutation | CLINVAR | p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: further evidence of CHK2 in inherited cancer predisposition. | 11479205 | 2001 |
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|
A | 0.700 | CausalMutation | CLINVAR | Novel germline mutation of the p53 tumor suppressor gene in a child with incidentally discovered adrenal cortical carcinoma. | 7978053 | 1994 |