Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs116264669
rs116264669
0.700 GeneticVariation GWASCAT Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis. 31092817

2019

dbSNP: rs1052133
rs1052133
0.020 GeneticVariation BEFREE In recent papers published by our group, we described the associations between the single nucleotide polymorphisms (SNPs) AADAT +401C > T, APEX1 Asn148Glu, OGG1 Ser326Cys and PARP1 Val762Ala and BM. 26316174

2015

dbSNP: rs1052133
rs1052133
0.020 GeneticVariation BEFREE For the SNP OGG1 Ser326Cys, the genotype Cys/Cys was more frequent (P<0.05) in BM group. 21651918

2011

dbSNP: rs352140
rs352140
0.020 GeneticVariation BEFREE We investigated whether bacterial meningitis (BM) in children was associated with gene polymorphisms in TLR2 (rs3804099), TLR3 (rs3775291 and rs3775290) and TLR9 (rs352139 and rs352140). 28202935

2017

dbSNP: rs352140
rs352140
0.020 GeneticVariation BEFREE We determined whether two common single nucleotide polymorphisms (SNPs) in the Toll-like receptor 9 gene (TLR9) (TLR9+2848 rs352140 and TLR9-1237 rs5743836) influenced susceptibility to bacterial meningitis in a Chinese population. 27525854

2016

dbSNP: rs1042714
rs1042714
0.010 GeneticVariation BEFREE We identified a functional polymorphism in ADRB2 (rs1042714) to be associated with an increased risk for bacterial meningitis (Odds ratio [OR] 1.35, 95% confidence interval [CI] 1.04-1.76; p = 0.026). 22624056

2012

dbSNP: rs1136410
rs1136410
0.010 GeneticVariation BEFREE In recent papers published by our group, we described the associations between the single nucleotide polymorphisms (SNPs) AADAT +401C > T, APEX1 Asn148Glu, OGG1 Ser326Cys and PARP1 Val762Ala and BM. 26316174

2015

dbSNP: rs17525495
rs17525495
0.010 GeneticVariation BEFREE We genotyped the LTA4H promoter region SNP (rs17525495) in 390 bacterial meningitis patients and 751 population controls. rs17525495 was associated with susceptibility to bacteriologically confirmed bacterial meningitis (P = 0.01, OR 1.27 95% confidence interval [CI] 1.05-1.54) but did not influence clinical presentation, disease severity or survival following dexamethasone treatment. 25799317

2015

dbSNP: rs17611
rs17611
C5
0.010 GeneticVariation BEFREE Here, we have performed a robust prospective nationwide genetic association study in patients with bacterial meningitis and found that a common nonsynonymous complement component 5 (C5) SNP (rs17611) is associated with unfavorable disease outcome. 21926466

2011

dbSNP: rs352139
rs352139
0.010 GeneticVariation BEFREE We investigated whether bacterial meningitis (BM) in children was associated with gene polymorphisms in TLR2 (rs3804099), TLR3 (rs3775291 and rs3775290) and TLR9 (rs352139 and rs352140). 28202935

2017

dbSNP: rs3775290
rs3775290
0.010 GeneticVariation BEFREE We investigated whether bacterial meningitis (BM) in children was associated with gene polymorphisms in TLR2 (rs3804099), TLR3 (rs3775291 and rs3775290) and TLR9 (rs352139 and rs352140). 28202935

2017

dbSNP: rs3775291
rs3775291
0.010 GeneticVariation BEFREE We investigated whether bacterial meningitis (BM) in children was associated with gene polymorphisms in TLR2 (rs3804099), TLR3 (rs3775291 and rs3775290) and TLR9 (rs352139 and rs352140). 28202935

2017

dbSNP: rs3804099
rs3804099
0.010 GeneticVariation BEFREE For TLR2 rs3804099, frequencies of the minor allele C were markedly higher in patients with severe BM (defined as CSF glucose concentration ≤ 1.5 mmol/L and seizures) than those without (43.5% and 40.1% vs. 30.1% and 29.1%, p = 0.008 and p = 0.016, respectively). 28202935

2017

dbSNP: rs5743836
rs5743836
0.010 GeneticVariation BEFREE However, no significant differences were observed in the association between the TLR9-1237 rs5743836 polymorphism and the risk of bacterial meningitis in the codominant, dominant, or recessive models. 27525854

2016

dbSNP: rs12081070
rs12081070
A 0.700 GeneticVariation GWASCAT Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis. 31092817

2019

dbSNP: rs2309554
rs2309554
A 0.700 GeneticVariation GWASCAT Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis. 31092817

2019

dbSNP: rs72739603
rs72739603
A 0.700 GeneticVariation GWASCAT Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis. 31092817

2019

dbSNP: rs3870369
rs3870369
T 0.700 GeneticVariation GWASCAT Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis. 31092817

2019