DisGeNET - a database of gene-disease associations

Essential Hypertension, C0085580

Variant: rs1799998 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1799998

CYP11B2

0.030

GeneticVariation

BEFREE

Overall, our meta-analysis suggested that rs1799998 polymorphism may serve as a potential biological marker of AF in East Asians and subjects with EH or HF.

30529851

2020

dbSNP:

rs1799998

CYP11B2

0.030

GeneticVariation

BEFREE

Among individuals with essential hypertension certain relationships were documented between rs5182 and rs5186 polymorphisms of AGTR1 gene and rs1799998 polymorphism of CYP11B2 gene on one hand and the volume of carotid bodies on one other.

29627490

2018

dbSNP:

rs1799998

CYP11B2

0.030

GeneticVariation

BEFREE

Significant association was also observed between rs1799998</span> (CYP11B2) and EH (P < 0.05) in the dominant, additive and allelic models.

25099490

2014