rs1034936
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest a role of rs1034936 CACNA1C gene variant in BD-AA group.
|
31634677 |
2020 |
rs13212041
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Determination of platelet 5-HT concentration and genotyping of rs13212041 <i>HTR1B</i> gene polymorphism were performed in 613 alcohol-dependent patients, subdivided according to early/late onset (before/after 25 years of age) of alcohol abuse.
|
30774345 |
2019 |
rs17817449
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated whether a tagging variant (rs17817449) within the FTO gene is associated with alcohol intake, problem drinking and smoking behaviour.
|
31055022 |
2019 |
rs12655166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Adjusting for multiple tests, one NR3C1 SNP (rs12655166) significantly moderated intervention effects on the developmental trajectories of alcohol abuse among AAs.
|
27817096 |
2018 |
rs1001179
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using an established PCR-RFLP method for genotyping, we examined the association of rs1001179 with glycated hemoglobin (HbA1c) and plasma lipids using univariate analyses with age, sex, body mass index (BMI), smoking, and alcohol abuse as covariates, in a group of dyslipidemic patients from northern Greece.
|
27704307 |
2017 |
rs2567608
|
|
|
0.010 |
GeneticVariation |
BEFREE |
None of following characteristics: current age, gender, term and kind of labor, 13 categories of childhood trauma, diet, alcohol drinking severity, age at alcohol drinking initiation, age at onset of problem drinking, cigarette smoking, and <i>SSTR4</i> rs2567608 was a significant predictor for <i>SSTR4</i> promoter region methylation.
|
29104801 |
2017 |
rs324420
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As this FAAH SNP has been reported to be associated with altered alcohol abuse, the present study used these genetic knock-in mice containing the human SNP C385A to determine the impact of variant FAAH gene on alcohol "binge" drinking in the drinking-in-the-dark (DID) model.
|
26857901 |
2016 |
rs53576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Oxytocin receptor gene variation rs53576 and alcohol abuse in a longitudinal population representative study.
|
27716573 |
2016 |
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The current study found that COMT rs4680 was related to both dimensionally and categorically measured gambling and drinking problems.
|
24390676 |
2015 |
rs17110747
|
|
|
0.010 |
GeneticVariation |
BEFREE |
More specifically, we observed that the T allele in the rs4570625 polymorphism was associated with psychotic disorders, and the A allele in the rs17110747 TPH2 polymorphism was associated with alcohol abuse in patients with TLE.
|
24491795 |
2014 |
rs1799971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association between the OPRM1 A118G (Asn40Asp, rs1799971) polymorphism and alcohol use disorders and alcohol consumption was analyzed using three different population-based samples: (a) a Finnish cohort study, Health 2000, with 503 participants having a DSM-IV diagnosis for alcohol dependence and/or alcohol abuse and 506 age- and sex-matched controls; (b) a Finnish cohort study, FINRISK (n = 2360) and (c) the Helsinki Birth Cohort Study (n = 1384).
|
23729673 |
2014 |
rs4570625
|
|
|
0.010 |
GeneticVariation |
BEFREE |
More specifically, we observed that the T allele in the rs4570625 polymorphism was associated with psychotic disorders, and the A allele in the rs17110747 TPH2 polymorphism was associated with alcohol abuse in patients with TLE.
|
24491795 |
2014 |
rs6265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The BDNF p.Val66Met polymorphism, childhood trauma, and brain volumes in adolescents with alcohol abuse.
|
25510982 |
2014 |
rs759834365
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The BDNF p.Val66Met polymorphism, childhood trauma, and brain volumes in adolescents with alcohol abuse.
|
25510982 |
2014 |
rs2306073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Concerning anxiety disorders and alcohol use disorders, the current findings are preliminary and need further verification to explain the association of ARNTL2, being suggestive only, with social phobia (rs2306073) and with alcohol abuse (rs7958822, rs4964057).
|
22538398 |
2012 |
rs671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among conventional markers of alcohol abuse, the mean corpuscular volume (MCV) of erythrocytes is prognostic of alcohol-related cancer and its predictivity increases when combined with functional polymorphisms of alcohol dehydrogenase (ADH1B [rs1229984] and ADH1C [rs698]) and the mitochondrial aldehyde dehydrogenase (ALDH2 [rs671]).
|
21917409 |
2012 |
rs698
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among conventional markers of alcohol abuse, the mean corpuscular volume (MCV) of erythrocytes is prognostic of alcohol-related cancer and its predictivity increases when combined with functional polymorphisms of alcohol dehydrogenase (ADH1B [rs1229984] and ADH1C [rs698]) and the mitochondrial aldehyde dehydrogenase (ALDH2 [rs671]).
|
21917409 |
2012 |
rs6350
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found significant evidence that the synonymous exon 2 rs6350 variant was positively associated with both alcohol consumption behavior (P=0.0004) and problem drinking (G allele, odds ratio: 3.63, 95% confidence interval: 1.22-10.78).
|
19352220 |
2009 |
rs348449
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, rs348449 is highly associated with problem drinking (allelic odds ratio [OR] 7.87, 95 per cent confidence interval [CI] 1.67-37.01) but due to the low minor allele frequency (0.01 and 0.07 in controls and problem drinkers, respectively), more samples are required to validate this observation.
|
19129088 |
2008 |
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genomic DNA from 103 patients with nontraumatic FHON (idiopathic in 50, steroid-induced in 29, and alcohol abuse in 24) and 103 control subjects matched for gender and age (3-year range) was analyzed for the 27-bp repeat polymorphism in intron 4 and Glu298Asp polymorphism in exon 7.
|
16779830 |
2006 |
rs1800562
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In Caucasians, C282Y HFE homozygotes are numerous, but they are only predisposed to hemochromatosis; complete organ disease develops in a minority, due to alcohol abuse or concurrent genetic modifiers that are now being identified.
|
26164493 |
2015 |
rs1800562
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Unlike these rare instances, in white people, homozygotes for C282Y polymorphism in HFE are numerous, but they are only predisposed to hemochromatosis; complete organ disease develops in a minority, when these individuals abuse alcohol or from other unidentified modifying factors.
|
20542038 |
2010 |
rs4964057
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Concerning alcohol use, the current findings give support, but are preliminary to, the associations of ARNTL (BMAL1) rs6486120 with alcohol consumption, ARNTL2 rs7958822 and ARNTL2 rs4964057 with alcohol abuse, and PER1 rs3027172 and PER2 rs56013859 with alcohol dependence.
|
25677407 |
2015 |
rs7958822
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Concerning alcohol use, the current findings give support, but are preliminary to, the associations of ARNTL (BMAL1) rs6486120 with alcohol consumption, ARNTL2 rs7958822 and ARNTL2 rs4964057 with alcohol abuse, and PER1 rs3027172 and PER2 rs56013859 with alcohol dependence.
|
25677407 |
2015 |
rs1229984
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Given the logistic and ethical constraints that would be associated with a trial of alcohol use to prevent depression, we aimed to complete a Mendelian randomization study to determine if a genetic polymorphism associated with alcohol abuse and dependence (ADH1B rs1229984 G-->A) contributed to modulate the risk of depression in a community-derived cohort of older men.
|
24018899 |
2014 |