DisGeNET - a database of gene-disease associations

Depressive Symptoms, C0086132

Variant: rs2230912 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs2230912

P2RX7 ; LOC105370032

0.020

GeneticVariation

BEFREE

Based on our findings, we propose that a P2RX7 haplotype combination of the Gln460Arg and neighboring SNPs contribute to the observed genetic association with depressive symptoms.

30664971

2019

dbSNP:

rs2230912

P2RX7 ; LOC105370032

0.020

GeneticVariation

BEFREE

After correcting for multiple testing, only the association of the P2RX7 Gln460Arg (rs2230912) polymorphism with depressive symptoms remained significant.

18801407

2008