|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, we assessed whether the functional single nucleotide polymorphism (SNP) on the BDNF gene, Val66Met, moderated the relationship between depressive symptoms and perceived social support and unsupportive relationships, and whether these associations differed by gender.
|
31364951 |
2020 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF (rs6265) and CRY1 (rs2287161) variants have been associated with more depressive symptoms in people with PD.
|
31292011 |
2020 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, we assessed whether the functional single nucleotide polymorphism (SNP) on the BDNF gene, Val66Met, moderated the relationship between depressive symptoms and perceived social support and unsupportive relationships, and whether these associations differed by gender.
|
31364951 |
2020 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The objective was to investigate if high cadence cycling altered non-motor cognition and depression symptoms in individuals with Parkinson's disease (PD) and whether exercise responses were influenced by brain-derived neurotrophic factor (BDNF) Val66Met polymorphism.
|
31197095 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The objective was to investigate if high cadence cycling altered non-motor cognition and depression symptoms in individuals with Parkinson's disease (PD) and whether exercise responses were influenced by brain-derived neurotrophic factor (BDNF) Val66Met polymorphism.
|
31197095 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results suggest a close relationship between job-related stress and depression, and the interaction of the BDNF Val66Met polymorphism and chronic stress in adulthood may impact the depressive symptoms.
|
29734099 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A BDNF Val66Met × Harsh Parenting interaction predicted the rise in depressive symptoms across a 3-year period, whereas a 5-HTTLPR × Harsh Parenting interaction predicted greater frequency in elevated depressive symptoms.
|
27736236 |
2018 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results suggest a close relationship between job-related stress and depression, and the interaction of the BDNF Val66Met polymorphism and chronic stress in adulthood may impact the depressive symptoms.
|
29734099 |
2018 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A BDNF Val66Met × Harsh Parenting interaction predicted the rise in depressive symptoms across a 3-year period, whereas a 5-HTTLPR × Harsh Parenting interaction predicted greater frequency in elevated depressive symptoms.
|
27736236 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our investigation assessed whether indices of white matter integrity, serotonin transporter-linked polymorphism (5-HTTLPR) and brain-derived neurotrophic factor (BDNF) val66met polymorphism predicted magnitude of depression symptom change following antidepressant treatment.
|
27277475 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
i) GG homozygotes (rs1475157-NRN1) showed higher scores on BSI depressive dimension and on total scores compared to A carriers (corrected p-values: 0.0004 and 0.0003, respectively). ii) a linear trend was detected between GG genotype of rs1475157 and a worse cognitive performance in WCST total correct responses (uncorrected p-value: 0.029). iii) Interaction between rs1475157-NRN1 and Val66Met-BDNF was found to modulate depressive symptoms (p=0.001, significant after correction).
|
28107668 |
2017 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
i) GG homozygotes (rs1475157-NRN1) showed higher scores on BSI depressive dimension and on total scores compared to A carriers (corrected p-values: 0.0004 and 0.0003, respectively). ii) a linear trend was detected between GG genotype of rs1475157 and a worse cognitive performance in WCST total correct responses (uncorrected p-value: 0.029). iii) Interaction between rs1475157-NRN1 and Val66Met-BDNF was found to modulate depressive symptoms (p=0.001, significant after correction).
|
28107668 |
2017 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our investigation assessed whether indices of white matter integrity, serotonin transporter-linked polymorphism (5-HTTLPR) and brain-derived neurotrophic factor (BDNF) val66met polymorphism predicted magnitude of depression symptom change following antidepressant treatment.
|
27277475 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There was a significant interaction between C-reactive protein (CRP) and the BDNF Val66met polymorphism in predicting cognitive depressive symptoms (p=.004), such that higher CRP was related to more cognitive depressive symptoms among Met allele carriers, but not among Val/Val homozygotes.
|
26967918 |
2016 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Among Aβ+ women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29).
|
27742526 |
2016 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Results indicated the BDNF Val66Met polymorphism significantly moderated the influence of maternal warmth-reasoning, but not harshness-hostility, on youth depressive symptoms.
|
26510938 |
2016 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Results indicated the BDNF Val66Met polymorphism significantly moderated the influence of maternal warmth-reasoning, but not harshness-hostility, on youth depressive symptoms.
|
26510938 |
2016 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There was a significant interaction between C-reactive protein (CRP) and the BDNF Val66met polymorphism in predicting cognitive depressive symptoms (p=.004), such that higher CRP was related to more cognitive depressive symptoms among Met allele carriers, but not among Val/Val homozygotes.
|
26967918 |
2016 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Among Aβ+ women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29).
|
27742526 |
2016 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study has provided the first examination of whether working memory capacity, the BDNF Val66Met polymorphism, and their interaction predict changes in symptoms of depression during the transition to university.
|
24920443 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We modeled the interactive effects of peer victimization with three genetic polymorphisms (on 5-HTTLPR, DRD2 TaqIA, and BDNF Val66Met) on depressive symptoms.
|
24819687 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study represents the first replication of the BDNF Val66Met ⁎ 5-HTTLPR ⁎ childhood maltreatment effect on self-reported depression symptoms using a rigorous maltreatment interview.
|
26070769 |
2015 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We modeled the interactive effects of peer victimization with three genetic polymorphisms (on 5-HTTLPR, DRD2 TaqIA, and BDNF Val66Met) on depressive symptoms.
|
24819687 |
2015 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study represents the first replication of the BDNF Val66Met ⁎ 5-HTTLPR ⁎ childhood maltreatment effect on self-reported depression symptoms using a rigorous maltreatment interview.
|
26070769 |
2015 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study has provided the first examination of whether working memory capacity, the BDNF Val66Met polymorphism, and their interaction predict changes in symptoms of depression during the transition to university.
|
24920443 |
2015 |