Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs118204057
rs118204057
LPL
0.030 GeneticVariation BEFREE The G188E, D9N, and N291S mutations in LPL increase TG, reduce HDL cholesterol, and increase risk of ischemic heart disease. 12208477

2002
dbSNP: rs118204057
rs118204057
LPL
0.030 GeneticVariation BEFREE Accordingly, risk of ischemic heart disease in heterozygous carriers is increased for Gly188Glu carriers; at most, the increase is borderline for Asp9Asn and Asn291Ser carriers; and risk is possibly decreased for Ser447Ter carriers. 10359734

1999
dbSNP: rs118204057
rs118204057
LPL
0.030 GeneticVariation BEFREE Heterozygous lipoprotein lipase deficiency due to the Gly188-->Glu substitution appears to increase plasma triglycerides and reduce HDL levels and may thereby predispose carriers to ischemic heart disease. 9323055

1997