Gene: STK11 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057520017
rs1057520017
STK11
T 0.700 GeneticVariation CLINVAR LKB1 modulates lung cancer differentiation and metastasis. 17676035

2007
dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR LKB1 modulates lung cancer differentiation and metastasis. 17676035

2007
dbSNP: rs1458974438
rs1458974438
STK11
0.030 GeneticVariation BEFREE In Kras<sup>LSL-G12D/WT</sup>, Kras<sup>LSL-G12D/WT</sup>; Lkb1<sup>Flox/Flox</sup> and Kras<sup>LSL-G12D/WT</sup>; p53<sup>Flox/Flox</sup> mouse models of lung adenocarcinoma, we monitored an impaired progression of tumors upon RANKL blockade. 29223537

2018
dbSNP: rs1458974438
rs1458974438
STK11
0.030 GeneticVariation BEFREE Here in Kras(G12D);Lkb1(lox/lox) (KL) mouse model, we reveal differential reactive oxygen species (ROS) levels in lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC). 25936644

2015
dbSNP: rs1458974438
rs1458974438
STK11
0.030 GeneticVariation BEFREE Conversely, YAP deletion dramatically delayed the progression of lung ADC in LKB1-deficient Kras(G12D) mice. 26363011

2015