rs113488022
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Here, we investigated the role played by (V600E)B-Raf in melanoma metastasis and showed that targeting this signaling cascade significantly reduces lung metastases.
|
16912199 |
2006 |
rs121913377
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Here, we investigated the role played by (V600E)B-Raf in melanoma metastasis and showed that targeting this signaling cascade significantly reduces lung metastases.
|
16912199 |
2006 |
rs113488022
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Results indicated that knockdown of mutant (V600E)B-Raf inhibited melanoma cell extravasation in vitro and subsequent lung metastasis development in vivo.
|
17575149 |
2007 |
rs121913377
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Results indicated that knockdown of mutant (V600E)B-Raf inhibited melanoma cell extravasation in vitro and subsequent lung metastasis development in vivo.
|
17575149 |
2007 |
rs113488022
|
|
|
0.050 |
GeneticVariation |
BEFREE |
B-Raf(V600E) cells in which either B-Raf(V600E) or TSP-1 were knocked down were implanted orthotopically into the thyroids of immunocompromised mice, resulting in significant reduction in tumor size and fewer pulmonary metastases from the primary carcinoma as compared with the control cells.
|
20498063 |
2010 |
rs121913377
|
|
|
0.050 |
GeneticVariation |
BEFREE |
B-Raf(V600E) cells in which either B-Raf(V600E) or TSP-1 were knocked down were implanted orthotopically into the thyroids of immunocompromised mice, resulting in significant reduction in tumor size and fewer pulmonary metastases from the primary carcinoma as compared with the control cells.
|
20498063 |
2010 |
rs121913227
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In melanoma, V600K mutations in comparison to other BRAF mutations were associated with more frequent brain (75% vs. 36.3%, p = 0.02) and lung metastases (91.6% vs. 47.7%, p = 0.007), and shorter time from diagnosis to metastasis and to death (19 vs. 53 months, p = 0.046 and 78 vs. 322 months, p = 0.024 respectively).
|
22039425 |
2011 |
rs113488022
|
|
|
0.050 |
GeneticVariation |
BEFREE |
NK cell frequencies were significantly enhanced by PLX4720 specifically in the lungs of mice with BRAF(V600E) lung metastases.
|
25351955 |
2014 |
rs121913377
|
|
|
0.050 |
GeneticVariation |
BEFREE |
NK cell frequencies were significantly enhanced by PLX4720 specifically in the lungs of mice with BRAF(V600E) lung metastases.
|
25351955 |
2014 |
rs113488022
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These findings suggest that the BRAF(V600E) mutation can be detected using a PNA clamp real-time PCR in the blood of PTC patients with lung metastasis.
|
25837167 |
2015 |
rs121913377
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These findings suggest that the BRAF(V600E) mutation can be detected using a PNA clamp real-time PCR in the blood of PTC patients with lung metastasis.
|
25837167 |
2015 |