Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800795
rs1800795
0.020 GeneticVariation BEFREE Two alleles were significantly associated with disc degeneration: IL-6 rs1800797 and MMP-9 rs17576 and one proved to be protective: IL-6 rs1800795. 28551829

2017

dbSNP: rs1800797
rs1800797
0.020 GeneticVariation BEFREE Two alleles were significantly associated with disc degeneration: IL-6 rs1800797 and MMP-9 rs17576 and one proved to be protective: IL-6 rs1800795. 28551829

2017

dbSNP: rs1800795
rs1800795
0.020 GeneticVariation BEFREE The risk of DD was significantly higher in subjects with an allele G of IL6 SNPs rs1800795 (OR 1.45, 95% CI 1.07-1.96) and rs1800797 (OR 1.37, 95% CI 1.02-1.85) in the additive inheritance model. 22107760

2011

dbSNP: rs1800797
rs1800797
0.020 GeneticVariation BEFREE The risk of DD was significantly higher in subjects with an allele G of IL6 SNPs rs1800795 (OR 1.45, 95% CI 1.07-1.96) and rs1800797</span> (OR 1.37, 95% CI 1.02-1.85) in the additive inheritance model. 22107760

2011

dbSNP: rs1800796
rs1800796
0.010 GeneticVariation BEFREE The role of IL6 was further supported by the haplotype analysis, which resulted in an association between the GGG haplotype (SNPs rs1800797, rs1800796 and rs1800795) and DD with an OR of 1.51 (95% CI 1.11-2.04). 22107760

2011