Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE Maternal C677T MTHFR polymorphism and environmental factors are associated with cleft lip and palate in a Mexican population. 23787444

2013
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE The common MTHFR C677T and A1298C variants are not associated with the risk of non-syndromic cleft lip/palate in northern Venezuela. 19447376

2009
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE Folate deficiency and the presence of the 677C > T (CT) polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene have been implicated in the causation of malformations in the fetus (particularly cleft lip and palate and neural tube defects). 17951123

2008
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE Family-based association study of the MTHFR polymorphism C677T in patients with nonsyndromic cleft lip and palate from central Europe. 18452350

2008
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. 16470725

2006