Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1466535
rs1466535
LRP1
0.840 GeneticVariation BEFREE Our work supports the evidence that the T allele of the rs1466535 LRP1 polymorphism is an independent risk factor for abdominal aortic aneurysm. 24423473

2015
dbSNP: rs1466535
rs1466535
LRP1
0.840 GeneticVariation BEFREE Genetic polymorphisms all previously reported as showing a significant correlation with AAA with functional effects on the expression or function were determined by analysis of the genomic DNA, including angiotensin 1 receptor (rs5186), interleukin-10 (IL-10; rs1800896), methyl-tetrahydrofolate reductase (rs1801133), low-density lipoprotein receptor-related protein 1 (LRP1; rs1466535), angiotensin-converting enzyme (rs1799752), and several matrix metalloproteinase 9 (MMP-9) single nucleotide polymorphisms. 24801553

2014
dbSNP: rs1466535
rs1466535
LRP1
0.840 GeneticVariation BEFREE An association between rs1466535 low density lipoprotein receptor-related protein 1 (LRP1) gene polymorphism and abdominal aortic aneurysm (AAA) was recently demonstrated. 25238221

2014
dbSNP: rs1466535
rs1466535
LRP1
C 0.840 GeneticVariation GWASDB No associations were seen for either rs1466535 or the 12q13.3 locus in independent association studies of coronary artery disease, blood pressure, diabetes, or hyperlipidaemia, suggesting that this locus is specific to AAA. 22055160

2011
dbSNP: rs1466535
rs1466535
LRP1
0.840 GeneticVariation BEFREE No associations were seen for either rs1466535 or the 12q13.3 locus in independent association studies of coronary artery disease, blood pressure, diabetes, or hyperlipidaemia, suggesting that this locus is specific to AAA. 22055160

2011
dbSNP: rs1466535
rs1466535
LRP1
C 0.840 GeneticVariation GWASCAT No associations were seen for either rs1466535 or the 12q13.3 locus in independent association studies of coronary artery disease, blood pressure, diabetes, or hyperlipidaemia, suggesting that this locus is specific to AAA. 22055160

2011
dbSNP: rs6511720
rs6511720
LDLR
T 0.810 GeneticVariation GWASCAT Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. 27899403

2017
dbSNP: rs6511720
rs6511720
LDLR
0.810 GeneticVariation GWASCAT LDLR rs6511720 is associated with AAA.This finding is consistent with established effects of this variant on coronary artery disease. 24046328

2013
dbSNP: rs6511720
rs6511720
LDLR
0.810 GeneticVariation GWASDB LDLR rs6511720 is associated with AAA.This finding is consistent with established effects of this variant on coronary artery disease. 24046328

2013
dbSNP: rs6511720
rs6511720
LDLR
0.810 GeneticVariation BEFREE LDLR rs6511720 is associated with AAA.This finding is consistent with established effects of this variant on coronary artery disease. 24046328

2013
dbSNP: rs7025486
rs7025486
DAB2IP
A 0.810 GeneticVariation GWASDB The A allele of rs7025486 on 9q33 was found to associate with AAA, with an odds ratio (OR) of 1.21 and P = 4.6 x 10(-10). 20622881

2010
dbSNP: rs7025486
rs7025486
DAB2IP
A 0.810 GeneticVariation GWASCAT The A allele of rs7025486 on 9q33 was found to associate with AAA, with an odds ratio (OR) of 1.21 and P = 4.6 x 10(-10). 20622881

2010
dbSNP: rs7025486
rs7025486
DAB2IP
0.810 GeneticVariation BEFREE The A allele of rs7025486 on 9q33 was found to associate with AAA, with an odds ratio (OR) of 1.21 and P = 4.6 x 10(-10). 20622881

2010
dbSNP: rs2383207
rs2383207
CDKN2B-AS1
G 0.800 GeneticVariation GWASCAT Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. 20622881

2010
dbSNP: rs2383207
rs2383207
CDKN2B-AS1
G 0.800 GeneticVariation GWASDB Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. 20622881

2010
dbSNP: rs2836411
rs2836411
ERG
0.720 GeneticVariation BEFREE Associations between rs9316871and rs2836411 and AAA risk were replicated in the meta-analysis of the two independent cohorts, providing further support for the importance of these loci in the aetiology of AAA. 31680049

2020
dbSNP: rs2836411
rs2836411
ERG
0.720 GeneticVariation BEFREE ERG is involved in vascular development, angiogenesis, and inflammation in atherosclerosis, therefore mechanistically, rs2836411 could contribute to AAA by modulating ERG levels. 31691800

2020
dbSNP: rs2836411
rs2836411
ERG
T 0.720 GeneticVariation GWASCAT Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. 27899403

2017
dbSNP: rs1795061
rs1795061 		0.710 GeneticVariation BEFREE In ARIC, rs9316871 and rs3827066 were significantly associated with AAA risk (HR [p] was 0.77 [.004] and 1.22 [.03], respectively), rs2836411 was associated at borderline significance (1.13 [.08]), whereas rs1795061 was not associated (p = .55). 31680049

2020
dbSNP: rs9316871
rs9316871 		0.710 GeneticVariation BEFREE In ARIC, rs9316871 and rs3827066 were significantly associated with AAA risk (HR [p] was 0.77 [.004] and 1.22 [.03], respectively), rs2836411 was associated at borderline significance (1.13 [.08]), whereas rs1795061 was not associated (p = .55). 31680049

2020
dbSNP: rs1795061
rs1795061 		T 0.710 GeneticVariation GWASCAT Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. 27899403

2017
dbSNP: rs9316871
rs9316871 		G 0.710 GeneticVariation GWASCAT Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. 27899403

2017
dbSNP: rs3019885
rs3019885
SLC30A8
0.710 GeneticVariation BEFREE The prevalence of carriers of the rs3019885 SLC30A8 G allele was higher in control subjects (67.8%) than in patients (60.3%, P = .022), suggesting a protective effect for AAA. 24423473

2015
dbSNP: rs3019885
rs3019885
SLC30A8
0.710 GeneticVariation GWASDB Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. 22055160

2011
dbSNP: rs10757274
rs10757274
CDKN2B-AS1
A 0.700 GeneticVariation GWASCAT Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. 27899403

2017