Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs843645
rs843645
0.020 GeneticVariation BEFREE Rs1682111 and rs843720 play a protective role in the additive model (rs1682111: OR = 0.69, 95% CI: 0.52-0.93, p = 0.01; rs843720: OR = 0.73, 95% CI: 0.54-0.98, p = 0.04).While rs843645 G allele increased the risk of cirrhosis developed into liver cancer under the additive model (OR = 1.42, 95% CI: 1.02-2.00, p = 0.04).The haplotype analysis detected that "ATATCGCC" decreased the risk of cirrhosis developed into liver cancer (OR = 0.69, 95% CI: 0.51-0.92, 95% CI: p = 0.013); however, "TGAGCGTC" increased the risk of cirrhosis developed into liver cancer (OR = 1.48, 95% CI: 1.04-2.10, p = 0.027). 31124313

2019

dbSNP: rs843645
rs843645
0.020 GeneticVariation BEFREE We found that rs6713088 (G allele: odds ratio [OR] = 1.27, 95% confidence interval [CI]: 1.07-1.52, <i>P</i> = 0.007; GG vs. CC: OR = 1.49, 95% CI: 1.02-2.1, <i>P</i> = 0.038), rs843711 (T allele: OR = 1.29, 95% CI: 1.09-1.54, <i>P</i> = 0.004; TT vs. CC: OR = 1.62, 95% CI: 1.13-2.31, <i>P</i> = 0.008), rs843706 (A allele: OR = 1.30, 95% CI: 1.09-1.55, <i>P</i> = 0.003; AA vs. CC: OR = 1.62, 95% CI: 1.13-2.31, <i>P</i> = 0.008), and rs843645 (GG vs. AG: OR = 1.40, 95% CI: 1.07-1.82, <i>P</i> = 0.014) were associated with an increased risk of liver cancer. 28978066

2017