Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE Pooled results indicated that neither C677T</span> nor A1298C polymorphism was associated with oral cancer susceptibility. 28138253

2017

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE The goals of this study were to evaluate the association of three genotypic polymorphism (MTHFR C677T, MTHFR A1298C and CBS 844ins68) and oral cancer risk in southeastern Brazilians and evaluate the interactions between polymorphisms and clinical histopathological parameters. 26749456

2016

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE These results suggest that MTHFR C677T polymorphism may play a role in oral cancer carcinogenesis in Asian population and heavy drinkers. 24488626

2014

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid). 24102947

2014

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE Polymorphisms of MTHFR C677T and A1298C association with oral carcinoma risk: a meta-analysis. 22536935

2012

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE Here we observed MTHFR C677T to influence oral cancer susceptibility, while A1298C polymorphism associated with patient prognosis. 20923444

2011

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE Those patients with MTHFR C677T CT and TT genotypes also had a lower risk of oral cancer metastasis. 21737671

2011

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE Interaction between the MTHFR C677T polymorphism and alcohol--impact on oral cancer risk and multiple DNA methylation of tumor-related genes. 20940365

2011

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico. 11925474

2002