|
rs243865
|
|
|
0.720 |
GeneticVariation |
BEFREE |
In this case-control study, MMP2 promoter 1306 (rs243865) and -735 (rs2285053) genotypes and their interaction with consumption of areca, cigarettes, and alcohol in determining oral cancer risk were investigated among 788 patients with oral cancer and 956 gender-matched healthy controls.
|
30504396 |
2018 |
|
rs243865
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Our data indicated genotypes and alleles in specific SNPs rs9849237, rs243865 and rs10090787 with increased/decreased risk to oral cancer.
|
28595731 |
2017 |
|
rs243865
|
|
T |
0.720 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs10090787
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Our data indicated genotypes and alleles in specific SNPs rs9849237, rs243865 and rs10090787 with increased/decreased risk to oral cancer.
|
28595731 |
2017 |
|
rs11130760
|
|
T |
0.710 |
GeneticVariation |
CLINVAR |
The SNP rs11130760 wild-type (WT) allele G indicated an increased risk for oral cancer (OR 1.38; 95% CI 1.09-1.73), whereas SNP allele T indicated a decreased risk (OR 0.73; 95% CI 0.58-0.92) for oral cancer.
|
28580594 |
2017 |
|
rs11130760
|
|
|
0.710 |
GeneticVariation |
BEFREE |
The SNP rs11130760 wild-type (WT) allele G indicated an increased risk for oral cancer (OR 1.38; 95% CI 1.09-1.73), whereas SNP allele T indicated a decreased risk (OR 0.73; 95% CI 0.58-0.92) for oral cancer.
|
28580594 |
2017 |
|
rs9849237
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Our data indicated genotypes and alleles in specific SNPs rs9849237, rs243865 and rs10090787 with increased/decreased risk to oral cancer.
|
28595731 |
2017 |
|
rs10090787
|
|
T |
0.710 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs9849237
|
|
T |
0.710 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1335022
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1957358
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs2124437
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs2306058
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs4512367
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Pooled results indicated that neither C677T</span> nor A1298C polymorphism was associated with oral cancer susceptibility.
|
28138253 |
2017 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The goals of this study were to evaluate the association of three genotypic polymorphism (MTHFR C677T, MTHFR A1298C and CBS 844ins68) and oral cancer risk in southeastern Brazilians and evaluate the interactions between polymorphisms and clinical histopathological parameters.
|
26749456 |
2016 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
These results suggest that MTHFR C677T polymorphism may play a role in oral cancer carcinogenesis in Asian population and heavy drinkers.
|
24488626 |
2014 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid).
|
24102947 |
2014 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Polymorphisms of MTHFR C677T and A1298C association with oral carcinoma risk: a meta-analysis.
|
22536935 |
2012 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Here we observed MTHFR C677T to influence oral cancer susceptibility, while A1298C polymorphism associated with patient prognosis.
|
20923444 |
2011 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Those patients with MTHFR C677T CT and TT genotypes also had a lower risk of oral cancer metastasis.
|
21737671 |
2011 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Interaction between the MTHFR C677T polymorphism and alcohol--impact on oral cancer risk and multiple DNA methylation of tumor-related genes.
|
20940365 |
2011 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico.
|
11925474 |
2002 |
|
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The best two-factor based G×G interaction of ora</span>l cancer included the XRCC1 rs1799782 and XRCC2 rs2040639 [OR=3.13, 95% CI=1.66-6.13].
|
25831063 |
2015 |
|
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The meta-analysis results suggest that the XRCC1 Arg399Gln and Arg280His polymorphisms are probably not associated with the risk of HNC, but the XRCC1 Arg194Trp polymorphism was associated with increased risk of HNC in the subgroup analysis of studies adjusted for smoking and alcohol and with increased risk of oral cancer in the stratified analyses based on cancer site.
|
24497981 |
2014 |