rs1273246817
|
|
|
0.010 |
GeneticVariation |
BEFREE |
S4153R is a gain-of-function mutation in the cardiac Ca(2+) release channel ryanodine receptor associated with catecholaminergic polymorphic ventricular tachycardia and paroxysmal atrial fibrillation.
|
23498838 |
2013 |
rs886037834
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
Bi-allelic Mutations in PKD1L1 Are Associated with Laterality Defects in Humans.
|
27616478 |
2016 |
rs16899974
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In coronary angiography patients without structural heart disease, the minor A allele of rs16899974 was associated with any AF (OR = 2.07, 95% CI 1.59-2.68), and with paroxysmal AF (OR = 1.98, 95% CI 1.44-2.74) and chronic AF (OR = 2.03, 95% CI 1.35-3.06) separately.
|
26984639 |
2016 |
rs372827955
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overexpression of p.R355C developed an atrial arrhythmia suggestive of paroxysmal AF in the zebrafish model.
|
26762269 |
2016 |
rs1011490341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through genetic studies, we showed that autosomal dominant early-onset nocturnal paroxysmal AF is caused by p.S447R mutation in KCND2, encoding the pore-forming (α) subunit of the Kv4.2 cardiac potassium channel.
|
30571183 |
2018 |
rs2106261
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, neutrophil/lymphocyte (N/L) ratio, C-reactive protein (CRP), and interleukin-6 (IL-6) expression levels were lower in PAF patients with the ZFHX3 SNP rs2106261 minor allele (TT+TC) than in CC patients (N/L ratio: CC 2.22 ± 0.08, TT+TC 1.98 ± 0.06, p = 0.018; CRP: CC 0.103 ± 0.009 mg/dl, TT+TC 0.076 ±0.007 mg/dl, p = 0.016; IL-6: CC 60.3 ± 3.0 pg/ml, TT+TC 52.8 ± 2.3 pg/ml, p = 0.04).
|
30180182 |
2018 |
rs10033464
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The combination of plasma TIMP-1 concentrations less than 107 ng/mL and the absence of a variant allele at rs10033464 was associated with lower recurrence rates in patients with paroxysmal AF.
|
31393025 |
2019 |
rs3745297
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We enrolled PAF patients who underwent RFCA (N = 334 for screening and N = 245 for replication) and were genotyped for HRC SNP (rs3745297).
|
30840693 |
2019 |