Logistic regression analysis showed that individuals carrying the TT genotype of XRCC4 rs2075685 had an increased risk of pancreatic cancer compared to those with the GG genotype, with an odds ratio (95% confidence interval) of 1.88 (1.15-3.08).
In conclusion, our results suggest that XRCC4 rs20</span>75685 polymorphism plays an important role in the risk of pancreatic cancer in a Chinese population, especially in tobacco smokers.