Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE The functional variants rs965513 and rs1867277 independently contribute to genetic predisposition to PTC, while a contributing role of the FOXE1 poly-Ala polymorphism could not be confirmed. 27824288

2017

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE There were significant associations of all SNPs with PTC (rs965513 odds ratio [OR] = 1.72, p = 8 × 10-7; rs1867277 OR = 1.59, p = 1 × 10-6; rs1443434 OR = 1.53, p = 1 × 10-5; rs944289 OR = 1.52, p = 4 × 10-5). 28660995

2017

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE We propose that the interaction between the lncRNA, its binding protein MYH9, and the coding gene FOXE1 underlies the predisposition to PTC triggered by rs965513. 28049826

2017

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE To evaluate the association between rs965513 and PTC in different ethnicities and countries, we conducted a meta-analysis using relatively large-scale samples from 23 studies (N = 163,136; 20,736 cases and 142,400 controls) by searching the PubMed and Google Scholar databases. 27191655

2016

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE We genotyped rs965513 from PTC patients and measured gene expression levels by real-time RT-PCR in unaffected thyroid tissue and matched tumor. 25303483

2015

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE Four GWAS-identified SNPs of papillary thyroid cancer (PTC), rs965513, rs944289, rs966423 and rs2439302, were genotyped in a case-control study of 838 patients with PTC and 501 patients with benign thyroid tumor (BTT) from the Chinese Han population. 25746573

2015

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE The [A] allele of SNP rs965513 in 9q22 has been consistently shown to be highly associated with increased papillary thyroid cancer (PTC</span>) risk with an odds ratio of ∼1.8 as determined by genome-wide association studies, yet the molecular mechanisms remain poorly understood. 25918370

2015

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE Similarly, the rs965513 on the TTF2 can also elevate the risk of PTC significantly (GA vs GG, OR = 1.67, 95% CI = 1.07-2.59; AA+GA vs AA, OR = 1.37, 95% CI = 1.09-1.82; A vs G, OR = 1.29, 95% CI = 1.05-1.59). 26356687

2015

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE The results showed significant associations of rs965513/rs944289 with PTC risk existed in overall population (for rs965513, A vs. G: OR 1.71 (1.56-1.86); for rs944289, T vs. C: OR 1.29 (1.23-1.37)). 24723258

2014

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE Four candidate loci, rs965513 (9q22.33), rs944289 (14q13.3), rs966423 (2q35) and rs2439302 (8p12), identified by GWAS for PTC risk were confirmed in a Chinese population. 23847140

2013

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE A genome-wide association study of papillary thyroid carcinoma (PTC) pinpointed two independent SNPs (rs944289 and rs965513) located in regions containing no annotated genes (14q13.3 and 9q22.33, respectively). 22586128

2012

dbSNP: rs965513
rs965513
0.100 GeneticVariation BEFREE The association of both rs965513 (p=1.27×10(-4), OR=1.69, 95% CI 1.29 to 2.21) and rs944289 (p=0.0121, OR=1.21, 95% CI 1.04 to 1.39) with the risk of sporadic PTC was confirmed. 21730105

2011