Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs146795390
rs146795390
EGFR
0.030 GeneticVariation BEFREE V843I, a lung cancer predisposing EGFR mutation, is responsible for resistance to EGFR tyrosine kinase inhibitors. 25057940

2014
dbSNP: rs146795390
rs146795390
EGFR
0.030 GeneticVariation BEFREE A dramatic lung cancer course in a patient with a rare EGFR germline mutation exon 21 V843I: Is EGFR TKI resistance predictable? 23380224

2013
dbSNP: rs146795390
rs146795390
EGFR
0.030 GeneticVariation BEFREE These observations suggest that the germline EGFR V843I mutation might have altered EGFR signaling in the multicentric development of adenocarcinoma, bronchoalveolar carcinoma, and atypical adenomatous hyperplasia and also might have had a role in the development of lung cancer in multiple members of her family. 18355544

2008